Arauridine

Arauridine

SCHEMBL359587

O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SLC28A1 O00337 1/20 1.00
▸ SLC28A2 O43868 1/20 1.00
▸ SLC29A1 Q99808 1/20 1.00
▸ SLC28A3 Q9HAS3 1/20 1.00
▸ P2RY2 P41231 11/20 0.69
▸ P2RY6 Q15077 8/20 0.65
▸ P2RY4 P51582 4/20 0.63
▸ P2RY14 Q15391 7/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uridine SCHEMBL14853938 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL2056533 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL329746 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL10815678 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL2056827 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL9060684 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL375985 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL7752140 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL20987631 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL1804774 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1568 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109727-A1 RNA CONSTRUCTS AND USES THEREOF BioNTech SE (DE) 2026-04-23 — — US claimed
US-12509698-B2 Synthesis and structure of high potency RNA therapeutics ARCTURUS THERAPEUTICS, INC. (US) 2025-12-30 — — US claimed
US-12496466-B2 Simulation-based drug treatment planning INSIGHTEC LTD. (IL) 2025-12-16 — — US claimed
EP-4634380-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-10-22 — — EP claimed
US-20250295744-A1 TREATMENT INVOLVING NON-IMMUNOGENIC RNA FOR ANTIGEN VACCINATION AND PD-1 AXIS BINDING ANTAGONISTS BioNTech SE (DE) 2025-09-25 — — US claimed
US-20250277223-A1 METHODS OF TREATING OR PREVENTING AUTOIMMUNE DISEASES IMCYSE SA (BE) 2025-09-04 — — US claimed
US-20250270299-A1 METHODS OF USING COMPOSITIONS COMPRISING SBI DOMAINS HELIX NANOTECHNOLOGIES INC 2025-08-28 — — US claimed
EP-3630985-B1 SYNTHESIS AND STRUCTURE OF HIGH POTENCY RNA THERAPEUTICS ARCTURUS THERAPEUTICS INC (US) 2025-08-27 — — EP claimed
EP-4606903-A1 METHOD FOR ENZYMATIC SYNTHESIS OF NUCLEOSIDE CONTAINING PROTECTING GROUP, AND COMPOSITION Asymchem Life Science (Tianjin) Co., Ltd (CN) 2025-08-27 — — EP claimed
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 — — US claimed
EP-1612213-A1 PROCESS FOR PRODUCING 2 -DEOXY-2 -FLUOROURIDINE Central Glass Company, Limited (JP) 2006-01-04 — — EP claimed
EP-1485395-A2 NUCLEOTIDE MIMICS AND THEIR PRODRUGS Biota, Inc. (US) 2004-12-15 — — EP claimed
WO-2003072757-A9 NUCLEOTIDE MIMICS AND THEIR PRODRUGS BIOTA INC (US) 2004-10-21 — — WO claimed
US-20040110718-A1 Anti-HCV nucleoside derivatives DEVOS RENE (GB) 2004-06-10 — — US claimed
US-20040059104-A1 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2004-03-25 — — US claimed
WO-2003072757-A2 NUCLEOTIDE MIMICS AND THEIR PRODRUGS BIOTA, INC. (US) 2003-09-04 — — WO claimed
EP-1315736-A2 NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C F. HOFFMANN-LA ROCHE AG (CH) 2003-06-04 — — EP claimed
US-20030008841-A1 Anti-HCV nucleoside derivatives F. HOFFMAN-LA ROCHE, A SWISS COMPANY (CH) 2003-01-09 — — US claimed
WO-2002018404-A2 NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C F. HOFFMANN-LA ROCHE AG (CH) 2002-03-07 — — WO claimed
US-4371613-A TRANSARABINOSYLATION USING AN ENZYME FROM BACTERIA, AN ARABINOSE DONOR AND A PURINE SOURCE AJINOMOTO COMPANY INCORPORATED (JP) 1983-02-01 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030008841-A1 Anti-HCV nucleoside derivatives PNP, HAVCR2, NUDT14 SLC28A1 28/4885SLC28A2 34/4885SLC29A1 18/4885
US-20040110718-A1 Anti-HCV nucleoside derivatives PNP, HAVCR2, NUDT14 SLC28A1 28/4885SLC28A2 34/4885SLC29A1 18/4885
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA RNASE1, POLRMT, TERT SLC28A1 1537/4885SLC28A2 1869/4885SLC29A1 1862/4885
US-12509698-B2 Synthesis and structure of high potency RNA therapeutics IGF2BP3, SERPINC1, IGF2BP2 SLC28A1 3845/4885SLC28A2 3161/4885SLC29A1 3727/4885
US-20040059104-A1 Nucleotide mimics and their prodrugs NUDT14, ENTPD5, MTAP SLC28A1 21/4885SLC28A2 33/4885SLC29A1 19/4885
US-20250270299-A1 METHODS OF USING COMPOSITIONS COMPRISING SBI DOMAINS C1QBP, SSB, SARNP SLC28A1 991/4885SLC28A2 1151/4885SLC29A1 949/4885
US-20260109727-A1 RNA CONSTRUCTS AND USES THEREOF RNGTT, RNMT, NSUN3 SLC28A1 684/4885SLC28A2 654/4885SLC29A1 799/4885
US-20250295744-A1 TREATMENT INVOLVING NON-IMMUNOGENIC RNA FOR ANTIGEN VACCINATION AND PD-1 AXIS BINDING ANTAGONISTS CD274, PDCD1LG2, PDCD1 SLC28A1 2912/4885SLC28A2 3579/4885SLC29A1 3842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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