Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.50 |
| ▸ | ITGAV | P06756 | 16/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 7/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6225174 | 0.92 | ITGB3 (0.50) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| Hydrochloric Acid SCHEMBL6223237 | 0.90 | ITGB3 (0.49) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL30073956 | 0.86 | ITGB3 (0.63) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL19090485 | 0.86 | KDM4E (0.48) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL6225428 | 0.86 | ITGB3 (0.63) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL6224327 | 0.82 | ADRA2A (0.55) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL15456444 | 0.79 | ADRA2A (0.48) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| Formic Acid SCHEMBL15456443 | 0.78 | ADRA2A (0.50) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7753126 | 0.77 | ADRA2A (0.58) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL19265544 | 0.76 | ITGB3 (0.63) | ITGB3ITGAVITGA2BITGB1ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070085-A1 | DUAL A v?b 3? AND METASTASIS-ASSOCIATED RECEPTOR LIGANDS | G.D. SEARLE & CO. (US) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999051638-A1 | DUAL Avb3 AND METASTASIS-ASSOCIATED RECEPTOR LIGANDS | G.D. SEARLE & CO. (US) | 1999-10-14 | — | — | WO | disclosed |