SCHEMBL7752219

SCHEMBL7752219

CS(=O)(=O)c1ccc(F)c([C]=O)c1

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.45
PTGS2 P35354 13/20 0.43
EPAS1 Q99814 1/20 0.43
KIF11 P52732 1/20 0.40
PTGS1 P23219 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27303724 0.85 PTGS2 (0.43) PTGS2EPAS1KIF11
SCHEMBL12327372 0.83 EPAS1 (0.55) PTGDR2PTGS2EPAS1PTGS1
SCHEMBL646030 0.77 PTGS2 (0.56) PTGS2KIF11PTGS1
SCHEMBL30041432 0.77 PTGS2 (0.56) PTGS2KIF11PTGS1
SCHEMBL2658282 0.77 PTGS2 (0.40) PTGS2KIF11PTGS1
SCHEMBL31704457 0.74 SMN1; SMN2 (0.55) PTGS2KIF11PTGS1
SCHEMBL2329775 0.74 PTGS2 (0.64) PTGS2PTGS1
SCHEMBL1631643 0.73 LMNA (0.47) PTGDR2PTGS2EPAS1
SCHEMBL27327668 0.73 EPAS1 (0.39) PTGS2EPAS1
SCHEMBL14146435 0.73 PTGS2 (0.43) PTGS2KIF11PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1071363-C Dyes, processes for their preparation and their use CIBA SC HOLDING AG (CH) 2001-09-19 CN disclosed
EP-0748850-B1 Dyestuffs, process for their preparation and their use CIBA SC HOLDING AG (CH) 2001-07-04 EP disclosed
EP-0828870-B1 SPIN DYEING PROCESS WITH DYEING SALTS DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-02-14 EP disclosed
CN-1054868-C Reactive dyes, processes for their preparation and their use CIBA SC HOLDING AG (CH) 2000-07-26 CN disclosed
CN-1054146-C Dye mixtures, processes for their preparation and their use CIBA SC HOLDING AG (CH) 2000-07-05 CN disclosed
CN-1046330-C Method for preparing and dyeing modified fibre materials HOECHST AG (DE) 1999-11-10 CN disclosed
EP-0625551-B1 Mixtures of dyes, process for their preparation and the use thereof CIBA GEIGY AG (CH) 1999-09-29 EP disclosed
EP-0631008-B1 Process for the washing of printings or dyeings on cellulose containing textile materials CIBA GEIGY AG (CH) 1999-08-18 EP disclosed
US-5938796-A Alkali system for dyeing cellulosic textiles by padding methods DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1999-08-17 US disclosed
US-5931975-A TRIAZINE REACTIVE DYES CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-08-03 US disclosed
EP-0209494-A1 Process for dyeing or printing with shade stability CIBA-GEIGY AG (CH) 1987-01-21 EP disclosed
CN-85107872-A The printing method of cellulose fibre (fabric) 1986-07-09 CN disclosed
EP-0181293-A2 Process for dyeing synthetic polyamide materials with anthrachinone reactive dyes CIBA-GEIGY AG (CH) 1986-05-14 EP disclosed
EP-0181292-A2 Process for the continuous trichromatic dyeing of synthetic polyamide materials CIBA-GEIGY AG (CH) 1986-05-14 EP disclosed
US-4588411-A Long-shelflife print containing reactive dye and alkali acetate pastes and their use CIBA-GEIGY CORPORATION (US) 1986-05-13 US disclosed
EP-0179019-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1986-04-23 EP disclosed
EP-0178255-A1 Process for fixing dyeings or printings CIBA-GEIGY AG (CH) 1986-04-16 EP disclosed
EP-0177449-A1 Process for printing cellulosic fibres CIBA-GEIGY AG (CH) 1986-04-09 EP disclosed
EP-0144093-A1 Storage-stable printing pastes and their use CIBA-GEIGY AG (CH) 1985-06-12 EP disclosed
EP-0131545-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-01-16 EP disclosed