Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 16/20 | 0.42 |
| ▸ | PDE4A | P27815 | 13/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 12/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978342 | 0.85 | PDE4B (0.44) | PDE4BPDE4APDE4CPDE4DSSTR5 | |
| Hydrochloric Acid SCHEMBL7032971 | 0.85 | PDE4B (0.43) | PDE4BPDE4APDE4CPDE4DSSTR5 | |
| SCHEMBL7380708 | 0.78 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6675072 | 0.74 | PDE4B (0.51) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL1388089 | 0.73 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL6154633 | 0.72 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3976102 | 0.71 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL27598340 | 0.69 | PDE4A (0.41) | PDE4BPDE4APDE4CPDE4DSSTR5 | |
| SCHEMBL2466398 | 0.69 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL30074724 | 0.69 | PDE4A (0.53) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310205-B1 | Hypoxathine compounds | EURO-CELTIQUE, S.A. (LU) | 2001-10-30 | — | — | US | disclosed |
| EP-0912575-A4 | IMPROVED METHODS FOR THE SYNTHESIS OF CHEMICAL COMPOUNDS HAVING PDE-IV INHIBITORY ACTIVITY | EURO CELTIQUE SA (LU) | 2001-04-25 | — | — | EP | disclosed |
| EP-0912575-A1 | IMPROVED METHODS FOR THE SYNTHESIS OF CHEMICAL COMPOUNDS HAVING PDE-IV INHIBITORY ACTIVITY | Euro-Celtique S.A. (LU) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997046561-A1 | IMPROVED METHODS FOR THE SYNTHESIS OF CHEMICAL COMPOUNDS HAVING PDE-IV INHIBITORY ACTIVITY | EURO-CELTIQUE, S.A. (LU) | 1997-12-11 | — | — | WO | disclosed |