Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 2/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897918 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MMP2CTSLCNR1CNR2 | |
| SCHEMBL6898112 | 0.92 | ALDH1A1 (0.41) | ALDH1A1MMP2CTSLITGA4ITGB7 | |
| SCHEMBL6897714 | 0.90 | ALDH1A1 (0.39) | ALDH1A1MMP2CTSLITGA4ITGB7 | |
| SCHEMBL6898016 | 0.86 | ALDH1A1 (0.47) | ALDH1A1CTSLITGA4ITGB7PTPN1 | |
| SCHEMBL27538243 | 0.85 | TACR2 (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL6891302 | 0.85 | TACR2 (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL6895846 | 0.84 | ALDH1A1 (0.48) | ALDH1A1CTSLITGA4ITGB7PTPN1 | |
| SCHEMBL6897716 | 0.84 | ALDH1A1 (0.46) | ALDH1A1CTSLITGA4ITGB7PTPN1 | |
| SCHEMBL6898396 | 0.84 | ALDH1A1 (0.45) | ALDH1A1CTSLITGA4ITGB7PTPN1 | |
| SCHEMBL6898114 | 0.83 | ALDH1A1 (0.42) | ALDH1A1CTSLITGA4ITGB7PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1072591-A1 | NOVEL UREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-01-31 | — | — | EP | disclosed |