Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897967 | 0.96 | ALDH1A1 (0.51) | ALDH1A1TMEM97SIGMAR1CTSLMEN1 | |
| SCHEMBL6894874 | 0.94 | ALDH1A1 (0.49) | ALDH1A1TMEM97SIGMAR1CTSLMEN1 | |
| SCHEMBL6898396 | 0.92 | ALDH1A1 (0.45) | ALDH1A1TMEM97SIGMAR1CTSLMEN1 | |
| SCHEMBL6895846 | 0.91 | ALDH1A1 (0.48) | ALDH1A1TMEM97SIGMAR1CTSLMEN1 | |
| SCHEMBL6897716 | 0.91 | ALDH1A1 (0.46) | ALDH1A1TMEM97SIGMAR1CTSLMEN1 | |
| SCHEMBL6891324 | 0.91 | TACR2 (0.44) | KMT2A | |
| SCHEMBL6890418 | 0.89 | ALDH1A1 (0.44) | ALDH1A1TMEM97SIGMAR1CTSLMEN1 | |
| SCHEMBL6897026 | 0.89 | L3MBTL1 (0.48) | — | |
| SCHEMBL7753429 | 0.88 | OPRM1 (0.49) | CTSL | |
| SCHEMBL6898098 | 0.88 | OPRM1 (0.49) | CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730784-B2 | AS THERAPEUTIC AGENTS FOR AUTOIMMUNE DISEASES SUCH AS RHEUMATOID ARTHRITIS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2004-05-04 | — | — | US | disclosed |
| EP-1395570-A1 | OXAZIN(THI)ONE COMPOUNDS USED AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-10 | — | — | EP | disclosed |
| EP-1315733-A2 | METHOD FOR PRODUCING ANELLATED TETRAHYDRO-[1H]-TRIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2003-06-04 | — | — | EP | disclosed |
| EP-1272475-A1 | 2-PHENYL-2H-PYRIDAZINE-3-ONES | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-08 | — | — | EP | disclosed |
| EP-1272476-A1 | 2-PHENYL-2H-PYRIDAZINE-3-ONES | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-08 | — | — | EP | disclosed |
| US-20020198376-A1 | Novel urea derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-26 | — | — | US | disclosed |
| US-6492370-B1 | Urea derivatives and pharmaceutical compositions thereof | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| WO-2002094797-A1 | OXAZIN(THI)ONE COMPOUNDS USED AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-28 | — | — | WO | disclosed |
| WO-2002069946-A2 | USE OF TRIAZOLE COMPOUNDS FOR PROPHYLAXIS AND IN THERAPY FOR NEURODEGENERATIVE ILLNESSES, BRAIN TRAUMAS AND CEREBRAL ISCHAEMIA | ABBOTT GMBH & CO. KG (DE) | 2002-09-12 | — | — | WO | disclosed |
| WO-2002069972-A2 | TRIAZOLE COMPOUNDS AND THE USE THEREOF IN THE PROPHYLAXIS AND THERAPY OF NEURODEGENERATIVE DISEASES, CEREBRAL TRAUMA AND CEREBRAL ISCHEMIA | ABBOTT GMBH & CO. KG (DE) | 2002-09-12 | — | — | WO | disclosed |
| WO-1998042682-A1 | NOVEL 1-AMINO-3 BENZYL URACILS | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-01 | — | — | WO | disclosed |
| EP-0835248-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997035845-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-02 | — | — | WO | disclosed |
| WO-1997030060-A1 | SUBSTITUTED AROMATIC PHOSPHONIC ACID DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1997-08-21 | — | — | WO | disclosed |
| WO-1997030059-A1 | SUBSTITUTED 2-PHENYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1997-08-21 | — | — | WO | disclosed |
| WO-1997001543-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |
| EP-0637298-A1 | SUBSTITUTED CYCLOHEXENE-1,2-BICARBOXYLIC ACID DERIVATIVES AND RAW MATERIALS FOR PRODUCING THEM | BASF Aktiengesellschaft (DE) | 1995-02-08 | — | — | EP | disclosed |
| EP-0604491-A1 | SUBSTITUTED 3-PHENYLURACILS AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1994-07-06 | — | — | EP | disclosed |
| EP-0599906-A1 | HERBICIDES CONTAINING 3-AMINOBENZO B]THIOPHENES AS AN ANTIDOTE. | BASF AG (DE) | 1994-06-08 | — | — | EP | disclosed |
| WO-1993006090-A1 | SUBSTITUTED 3-PHENYLURACILS AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198376-A1 | Novel urea derivatives | TNF, CTH, CFH | ALDH1A1 1309/4885TMEM97 1439/4885SIGMAR1 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.