Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.50 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27462865 | 0.85 | ITGB3 (0.60) | ITGB3ITGA2BITGAV | |
| SCHEMBL7752379 | 0.85 | ITGB3 (0.60) | ITGB3ITGA2BITGAV | |
| SCHEMBL27464161 | 0.80 | ITGB3 (0.66) | ITGB3ITGA2B | |
| SCHEMBL27451238 | 0.79 | ITGB3 (0.60) | ITGB3ITGA2BITGAV | |
| SCHEMBL7752595 | 0.79 | ITGB3 (0.60) | ITGB3ITGA2BITGAV | |
| SCHEMBL27450350 | 0.78 | ITGB3 (0.63) | ITGB3ITGA2B | |
| SCHEMBL7748771 | 0.77 | ITGB3 (0.62) | ITGB3ITGA2B | |
| SCHEMBL7752672 | 0.75 | MMP13 (0.45) | MMP2MMP9MMP8 | |
| SCHEMBL7753699 | 0.75 | ITGB3 (0.54) | ITGB3ITGA2BITGAV | |
| SCHEMBL8190476 | 0.75 | ITGB3 (0.57) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-B1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMA (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |