SCHEMBL7752471

SCHEMBL7752471

[SiH3]C1C(c2cccs2)=Cc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
KDM4E B2RXH2 7/20 0.33
MEN1 O00255 5/20 0.33
KMT2A Q03164 5/20 0.33
HSD17B10 Q99714 5/20 0.33
L3MBTL1 Q9Y468 4/20 0.33
NPC1 O15118 4/20 0.33
RAB9A P51151 4/20 0.33
HPGD P15428 3/20 0.33
MAPT P10636 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7752884 0.78 CHRM2 (0.35) CHRM2CHRM4CHRM5CHRM1CHRM3
Hydrochloric Acid SCHEMBL7064763 0.78 CHRM2 (0.35) CHRM2CHRM4CHRM5CHRM1CHRM3
Hydrochloric Acid SCHEMBL7064893 0.77 CHRM2 (0.34) CHRM2CHRM4CHRM5CHRM1CHRM3
Hydrochloric Acid SCHEMBL7062670 0.77 CHRM2 (0.34) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL7062671 0.76 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL7064894 0.76 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL7752887 0.76 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL7064765 0.76 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL7177990 0.76 RAB9A (0.36) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL7858858 0.73 CHRM2 (0.32) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1293676-A Metallocene compounds as catalyst components for olefin polymerization CHISSO CORP (JP) 2001-05-02 CN disclosed
EP-1066300-A1 METALLOCENE COMPOUNDS AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION Chisso Corporation (JP) 2001-01-10 EP disclosed
WO-2000043406-A1 METALLOCENE COMPOUNDS AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION CHISSO CORPORATION (JP) 2000-07-27 WO disclosed