Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.35 |
| ▸ | PTAFR known ✓ | P25105 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7064763 | 0.80 | CHRM2 (0.35) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL7064893 | 0.79 | CHRM2 (0.34) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL7062670 | 0.79 | CHRM2 (0.34) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7752471 | 0.78 | CHRM2 (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7062671 | 0.74 | CHRM2 (0.33) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7177990 | 0.74 | RAB9A (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7752887 | 0.74 | CHRM2 (0.33) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7064765 | 0.74 | CHRM2 (0.33) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7064894 | 0.74 | CHRM2 (0.33) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL4459246 | 0.73 | LMNA (0.31) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631591-B | Process for producing catalyst component for olefin polymerization, process for producing catalyst for olefin polymerization, and process for producing olefin polymer | 日本聚丙烯株式会社 | 2023-05-05 | — | — | CN | disclosed |
| WO-2022059765-A1 | METHOD FOR PRODUCING ION-EXCHANGEABLE LAYERED SILICATE SALT PARTICLES, METHOD FOR PRODUCING OLEFIN POLYMERIZATION CATALYST COMPONENT, METHOD FOR PRODUCING OLEFIN POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING OLEFIN POLYMER USING SAME | 日本ポリプロ株式会社 | 2022-03-24 | — | — | WO | disclosed |
| CN-113631591-A | Method for producing catalyst component for olefin polymerization, method for producing catalyst for olefin polymerization, and method for producing olefin polymer | 日本聚丙烯株式会社 | 2021-11-09 | — | — | CN | disclosed |
| WO-2020203274-A1 | PRODUCTION METHOD FOR CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PRODUCTION METHOD FOR CATALYST FOR OLEFIN POLYMERIZATION, AND PRODUCTION METHOD FOR OLEFIN POLYMER | 日本ポリプロ株式会社 | 2020-10-08 | — | — | WO | disclosed |
| EP-1066300-A1 | METALLOCENE COMPOUNDS AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | Chisso Corporation (JP) | 2001-01-10 | — | — | EP | disclosed |
| WO-2000043406-A1 | METALLOCENE COMPOUNDS AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | CHISSO CORPORATION (JP) | 2000-07-27 | — | — | WO | disclosed |