Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 9/20 | 0.36 |
| ▸ | CA2 | P00918 | 9/20 | 0.36 |
| ▸ | CA9 | Q16790 | 8/20 | 0.36 |
| ▸ | CA12 | O43570 | 7/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL985487 | 0.83 | RORA (0.47) | RORARORCNR1H2NLRP3PFKFB3 | |
| SCHEMBL19391630 | 0.81 | RORA (0.46) | RORARORCNR1H2NLRP3PFKFB3 | |
| SCHEMBL4309721 | 0.81 | RORA (0.46) | RORARORCNR1H2NLRP3PFKFB3 | |
| SCHEMBL3193197 | 0.81 | RORA (0.49) | RORARORCNR1H2NLRP3PFKFB3 | |
| Ammonia Solution, Strong SCHEMBL591654 | 0.80 | RORA (0.48) | RORARORCNR1H2NLRP3PFKFB3 | |
| SCHEMBL2728455 | 0.79 | MEN1 (0.41) | CA1CA2CA9CA12CA4 | |
| SCHEMBL571688 | 0.78 | TET2 (0.46) | RORARORCNR1H2CA1CA2 | |
| SCHEMBL3498898 | 0.77 | RORA (0.52) | RORARORCNR1H2NLRP3PFKFB3 | |
| SCHEMBL3501251 | 0.77 | HDAC3 (0.45) | RORARORCNR1H2NLRP3PFKFB3 | |
| SCHEMBL19269465 | 0.77 | MAPT (0.42) | RORARORCNR1H2NLRP3PFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001047485-A1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-07-05 | — | — | WO | claimed |
| WO-2015104433-A1 | BENZO[C][1,2,5]OXADIAZOLE DERIVATIVES FOR TREATING DISEASES CAUSED BY HELICOBACTER | UNIVERSIDAD DE ZARAGOZA (ES) | 2015-07-16 | — | — | WO | disclosed |
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | disclosed |
| WO-2006002284-A1 | UBIQUITIN LIGASE INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2006-01-05 | — | — | WO | disclosed |