SCHEMBL985487

SCHEMBL985487

O=S(=O)(Cl)c1ccc(Cl)c2nonc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORA P35398 1/20 0.47
RORC P51449 1/20 0.47
NR1H2 P55055 1/20 0.47
NLRP3 Q96P20 1/20 0.46
PFKFB3 Q16875 1/20 0.41
TRPV4 Q9HBA0 2/20 0.37
ALDH1A1 P00352 6/20 0.33
LMNA P02545 4/20 0.33
NPC1 O15118 3/20 0.33
TLR9 Q9NR96 3/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
HSD17B10 Q99714 2/20 0.33
HTT P42858 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TP53 P04637 1/20 0.33
XBP1 P17861 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4309721 0.98 RORA (0.46) RORARORCNR1H2NLRP3PFKFB3
SCHEMBL3193197 0.83 RORA (0.49) RORARORCNR1H2NLRP3PFKFB3
SCHEMBL3501293 0.83 RORA (0.35) RORARORCNR1H2NLRP3PFKFB3
SCHEMBL7752552 0.83 RORA (0.46) RORARORCNR1H2NLRP3PFKFB3
SCHEMBL19391630 0.83 RORA (0.46) RORARORCNR1H2NLRP3PFKFB3
Ammonia Solution, Strong SCHEMBL591654 0.81 RORA (0.48) RORARORCNR1H2NLRP3PFKFB3
SCHEMBL10693669 0.79 POLB (0.37) RORARORCNR1H2NLRP3TRPV4
SCHEMBL19143549 0.79 POLB (0.36) RORARORCNR1H2NLRP3TRPV4
SCHEMBL3498898 0.79 RORA (0.52) RORARORCNR1H2NLRP3PFKFB3
SCHEMBL3501251 0.79 HDAC3 (0.45) RORARORCNR1H2NLRP3PFKFB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115521335-A Synthesis and application of bifunctional fluorescent probe capable of distinguishing peroxy anion and cysteine simultaneously 湖南师范大学 2022-12-27 CN claimed
CN-113264898-B Benzoxazole colorimetric fluorescent probe ZY15 for detecting mercury ions and preparation method and application thereof 湖北理工学院 2022-05-06 CN claimed
CN-114195731-A Hydrogenated nitrosyl donor compound and preparation method thereof 海南大学 2022-03-18 CN claimed
CN-112266366-B Nitrofuran derivative-based fluorescent molecule for formaldehyde detection and preparation method and application thereof 河南省农业科学院农业质量标准与检测技术研究所 2022-03-18 CN claimed
CN-113264898-A Benzoxazole colorimetric fluorescent probe ZY15 for detecting mercury ions and preparation method and application thereof 湖北理工学院 2021-08-17 CN claimed
CN-112266366-A Nitrofuran derivative-based fluorescent molecule for formaldehyde detection and preparation method and application thereof 河南省农业科学院农业质量标准与检测技术研究所 2021-01-26 CN claimed
CN-106939015-B A kind of malonaldehyde fluorescence probe and its preparation method and application 济南大学 2018-12-18 CN claimed
CN-106939015-A A kind of MDA fluorescence probe and its preparation method and application 济南大学 2017-07-11 CN claimed
US-8885135-B2 Nanostructure-film LCD devices SAMSUNG ELECTRONICS CO., LTD. (KR) 2014-11-11 US claimed
US-20120308771-A1 NANOSTRUCTURE FILMS DRAZAIC PAUL (US) 2012-12-06 US claimed
JP-2011527809-A 2011-11-04 JP claimed
WO-2009152146-A1 IMPROVED CNT/TOPCOAT PROCESSES FOR MAKING A TRANSPLANT CONDUCTOR UNIDYM, INC. (US) 2009-12-17 WO claimed
US-20090147167-A1 Nanostructure-Film LCD Devices SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-06-11 US claimed
WO-2009058763-A1 NANOSTRUCTURE-FILM LCD DEVICES UNIDYM, INC. (US) 2009-05-07 WO claimed
JP-9278765-A None JP disclosed
US-20250339388-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF MAXYMUNE THERAPEUTICS INC (US) 2025-11-06 US disclosed
US-20250319046-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF MAXYMUNE THERAPEUTICS INC (US) 2025-10-16 US disclosed
EP-1283831-A1 INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 BIOVITRUM AB (SE) 2003-02-19 EP disclosed
WO-2001090090-A1 INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 BIOVITRUM AB (SE) 2001-11-29 WO disclosed
JP-H09278765-A NOVEL 2,1,3-BENZOXADIAZOLE DERIVATIVE TOKYO KASEI KOGYO KK 1997-10-28 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250339388-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF SLC43A1, SLC7A1, SLC1A5 RORA 3173/4885RORC 2739/4885NR1H2 2639/4885
US-20250319046-A1 PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF SLC43A1, SLC7A1, SLC1A5 RORA 3173/4885RORC 2739/4885NR1H2 2639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.