Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9462115 | 1.00 | THRB (0.46) | THRBLMNACYP3A4USP2SMN1; SMN2 | |
| SCHEMBL19206303 | 1.00 | THRB (0.46) | THRBLMNACYP3A4USP2SMN1; SMN2 | |
| SCHEMBL9462521 | 1.00 | THRB (0.46) | THRBLMNACYP3A4USP2SMN1; SMN2 | |
| SCHEMBL9462430 | 1.00 | THRB (0.46) | THRBLMNACYP3A4USP2SMN1; SMN2 | |
| SCHEMBL29602471 | 1.00 | THRB (0.46) | THRBLMNACYP3A4USP2SMN1; SMN2 | |
| SCHEMBL9462317 | 1.00 | THRB (0.46) | THRBLMNACYP3A4USP2SMN1; SMN2 | |
| SCHEMBL31558046 | 0.97 | THRB (0.48) | THRBLMNACYP3A4USP2SMN1; SMN2 | |
| SCHEMBL4196461 | 0.92 | THRB (0.48) | THRBLMNACYP3A4USP2SMN1; SMN2 | |
| SCHEMBL28900807 | 0.91 | THRB (0.44) | THRBLMNACYP3A4USP2SMN1; SMN2 | |
| SCHEMBL11148803 | 0.86 | LMNA (0.50) | LMNAACACBACACATRPV1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001039766-A2 | SCREENING INVERTEBRATE PHEROMONES FOR THERAPEUTIC ACTIVITY | ALYDAR PHARMACEUTICALS LTD. (IL) | 2001-06-07 | — | — | WO | claimed |
| US-5190978-A | Carcinostatic compositions and methods | DAI-ICHI KOGYO SEIYAKU CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |