SCHEMBL7752564

SCHEMBL7752564

Nc1ccc(C2CCC(Cc3ccccc3)CC2)cc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
GBA1 P04062 1/20 0.49
PRMT3 O60678 1/20 0.45
CARM1 Q86X55 1/20 0.45
PRMT6 Q96LA8 1/20 0.45
PRMT1 Q99873 1/20 0.45
PRMT8 Q9NR22 1/20 0.45
CCR3 P51677 2/20 0.45
IDO1 P14902 1/20 0.43
MAOA P21397 2/20 0.42
MAOB P27338 2/20 0.42
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
NOS2 P35228 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7752419 0.94 MEN1 (0.48) MEN1KMT2AGBA1PRMT3CARM1
SCHEMBL27533679 0.87 GBA1 (0.57) GBA1PRMT3CARM1PRMT6PRMT1
SCHEMBL7926781 0.83 ACHE (0.42) MEN1KMT2A
SCHEMBL7747132 0.83 SPHK1 (0.41) MEN1KMT2A
SCHEMBL7747016 0.81 SPHK1 (0.49) MEN1KMT2A
SCHEMBL2608099 0.80 MEN1 (0.40) MEN1KMT2AGBA1PRMT3CARM1
SCHEMBL7753727 0.80 CYP3A4 (0.41) MEN1KMT2A
SCHEMBL7752506 0.80 CYP3A4 (0.41) MEN1KMT2A
SCHEMBL7446113 0.79 MEN1 (0.49) MEN1KMT2AGBA1MAOAMAOB
SCHEMBL5592675 0.79 GBA1 (0.49) GBA1CCR3IDO1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101195711-A Polyamic acid composition and alignment film prepared from same DALI POLYMER CO LTD (CN) 2008-06-11 CN disclosed
EP-1064329-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2001-01-03 EP disclosed
EP-1064319-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2001-01-03 EP disclosed
EP-1042701-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2000-10-11 EP disclosed
WO-1999033902-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1999-07-08 WO disclosed
WO-1999033923-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1999-07-08 WO disclosed
WO-1999034252-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1999-07-08 WO disclosed