SCHEMBL7752603

SCHEMBL7752603

CONCc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)ccc1Cl

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
AR P10275 1/20 0.30
BRD9 Q9H8M2 1/20 0.30
IDH1 O75874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8173601 0.91
SCHEMBL7755886 0.89 BRD9 (0.31) MEN1KMT2ABRD9
SCHEMBL7757110 0.87 POLB (0.32) MEN1KMT2A
SCHEMBL8173603 0.85 RXFP1 (0.31)
SCHEMBL9423157 0.83 RORC (0.35) MEN1KMT2AARBRD9
SCHEMBL7757118 0.83 MEN1 (0.31) MEN1KMT2ABRD9
SCHEMBL8173609 0.81
SCHEMBL14571462 0.79 BRD9 (0.41) BRD9
SCHEMBL7162858 0.79
SCHEMBL7894565 0.78 ITGB1 (0.31) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0836594-B1 BENZYLHYDROXYLAMINES AND INTERMEDIATES USED TO PREPARE THEM BASF AG (DE) 2001-03-07 EP disclosed
US-6057269-A HERBICIDES AND FOR THE DESICCATION/DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 2000-05-02 US disclosed
CN-1192737-A Benzylhydroxylamines and intermediates used to prepare them BASF AG (DE) 1998-09-09 CN disclosed
WO-1997002253-A1 BENZYLHYDROXYLAMINES AND INTERMEDIATES USED TO PREPARE THEM BASF AKTIENGESELLSCHAFT (DE) 1997-01-23 WO disclosed