SCHEMBL7755886

SCHEMBL7755886

CCONCc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)ccc1Cl

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BRD9 Q9H8M2 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7752603 0.89 MEN1 (0.31) BRD9MEN1KMT2A
SCHEMBL7757110 0.83 POLB (0.32) MEN1KMT2A
SCHEMBL9423157 0.81 RORC (0.35) BRD9MEN1KMT2A
SCHEMBL8173601 0.80
SCHEMBL10576364 0.79 CCR1 (0.39) BRD9
SCHEMBL7757118 0.79 MEN1 (0.31) BRD9MEN1KMT2A
SCHEMBL7894565 0.76 ITGB1 (0.31) MEN1KMT2A
SCHEMBL13693064 0.76 PTGS1 (0.37) BRD9
SCHEMBL9423300 0.76 MEN1 (0.31) MEN1KMT2A
SCHEMBL6699195 0.76 CYP4F2 (0.44) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0836594-B1 BENZYLHYDROXYLAMINES AND INTERMEDIATES USED TO PREPARE THEM BASF AG (DE) 2001-03-07 EP disclosed
US-6057269-A HERBICIDES AND FOR THE DESICCATION/DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 2000-05-02 US disclosed
CN-1192737-A Benzylhydroxylamines and intermediates used to prepare them BASF AG (DE) 1998-09-09 CN disclosed
WO-1997002253-A1 BENZYLHYDROXYLAMINES AND INTERMEDIATES USED TO PREPARE THEM BASF AKTIENGESELLSCHAFT (DE) 1997-01-23 WO disclosed