Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.54 |
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | NPY4R | P50391 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569755 | 1.00 | FOLH1 (0.58) | FOLH1OPRM1OPRD1BACE1BACE2 | |
| SCHEMBL30123119 | 0.86 | OPRD1 (0.66) | OPRM1OPRD1BACE1BACE2OPRK1 | |
| SCHEMBL30073211 | 0.85 | FOLH1 (0.65) | FOLH1OPRM1OPRD1NPY1RNPY2R | |
| SCHEMBL7752844 | 0.85 | CASP1 (0.55) | FOLH1OPRD1BACE1BACE2CASP1 | |
| SCHEMBL29886195 | 0.84 | BACE1 (0.55) | OPRM1OPRD1BACE1BACE2REN | |
| SCHEMBL30423308 | 0.84 | FOLH1 (0.71) | FOLH1NPY1RNPY2RNPY4RACE | |
| SCHEMBL30845367 | 0.84 | FOLH1 (0.71) | FOLH1NPY1RNPY2RNPY4RACE | |
| SCHEMBL22498360 | 0.84 | FOLH1 (0.71) | FOLH1NPY1RNPY2RNPY4RACE | |
| SCHEMBL8332107 | 0.84 | FOLH1 (0.58) | FOLH1OPRM1OPRD1BACE1BACE2 | |
| SCHEMBL8332105 | 0.84 | FOLH1 (0.58) | FOLH1OPRM1OPRD1BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146614-A | TREATMENT OF SCHIZOPHRENIA | STATE OF MICHIGAN (US) | 1979-03-27 | — | — | US | disclosed |