SCHEMBL7752958

SCHEMBL7752958

Cc1[c]cc(C)c(S(=O)(=O)O)c1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.37
TP53 P04637 1/20 0.34
CREBBP Q92793 1/20 0.34
POLB P06746 1/20 0.33
RECQL P46063 1/20 0.33
ESR2 Q92731 1/20 0.33
MYC P01106 1/20 0.32
CASR P41180 1/20 0.31
SUMO2 P61956 1/20 0.30
SUMO1 P63165 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP3 Q9H4L4 1/20 0.30
SENP2 Q9HC62 1/20 0.30
SENP1 Q9P0U3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10485523 0.85 MYC (0.32) BRD4TP53POLBRECQLMYC
SCHEMBL8829803 0.83 BRD4 (0.40) BRD4TP53CREBBPPOLBRECQL
SCHEMBL10508320 0.82 BRD4 (0.36) BRD4TP53CREBBPPOLBRECQL
SCHEMBL9169863 0.82 HSD17B10 (0.39) BRD4TP53CREBBPMYC
SCHEMBL1377271 0.77 BRD4 (0.33) BRD4TP53CREBBPPOLBRECQL
SCHEMBL28139201 0.76 ALDH1A1 (0.33) MYC
SCHEMBL8469963 0.74 BRD4 (0.48) BRD4TP53CREBBPPOLBRECQL
SCHEMBL3395151 0.72 BRD4 (0.52) BRD4TP53CREBBPPOLBRECQL
SCHEMBL2862138 0.70 BRD4 (0.50) BRD4TP53CREBBPPOLBRECQL
SCHEMBL5049711 0.69 BRD4 (0.39) BRD4TP53CREBBPMYCCASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0719841-B1 Mixture of water soluble reactive azo dyes, process to manufacture it and its use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-03-14 EP disclosed
US-5980590-A HIGH COLOR YIELD; FOR DYEING OR PRINTING OF CELLULOSIC FIBERS, WOOL, AND POLYAMIDE FIBERS DYSTAR TEXILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1999-11-09 US disclosed
US-5629409-A Reactive disazo dyes having two cyanuric chloride mechanisms BASF AKTIENGESELLSCHAFT (DE) 1997-05-13 US disclosed
EP-0719841-A1 Mixture of water soluble reactive azo dyes, process to manufacture it and its use HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-03 EP disclosed
CN-1113508-A Reactive disazo dyes having two cyanuric chloride mechanisms BASF AG (DE) 1995-12-20 CN disclosed
EP-0671442-A2 Disazo reactive dyes having two anchors based on cyanuric chloride BASF AKTIENGESELLSCHAFT (DE) 1995-09-13 EP disclosed