Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5049711 | 0.84 | BRD4 (0.39) | BRD4TP53CREBBPMYCCASR | |
| SCHEMBL2468059 | 0.83 | — | — | |
| SCHEMBL7752958 | 0.82 | BRD4 (0.37) | BRD4TP53CREBBPPOLBRECQL | |
| SCHEMBL6633299 | 0.81 | LMNA (0.31) | LMNAHPGDHIF1AHSD17B10 | |
| SCHEMBL9167903 | 0.80 | BRD4 (0.33) | BRD4TP53CREBBPHPGDHIF1A | |
| SCHEMBL5509341 | 0.78 | CA12 (0.31) | — | |
| SCHEMBL6142173 | 0.78 | HSD17B10 (0.40) | LMNAHPGDHIF1AHSD17B10 | |
| SCHEMBL10646743 | 0.76 | TTR (0.36) | BRD4TP53CREBBPPOLBRECQL | |
| SCHEMBL10504821 | 0.76 | ALDH1A1 (0.39) | TP53POLBRECQLLMNAHPGD | |
| SCHEMBL1377271 | 0.76 | BRD4 (0.33) | BRD4TP53CREBBPPOLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190603-B1 | AMINOALKYLENESULFONE-TRIPHENEDIOXAZINE DYES | BAYER AG (DE) | 1989-03-22 | — | — | EP | disclosed |
| US-4806640-A | Triphendioxazine reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-21 | — | — | US | disclosed |
| EP-0205080-B1 | TRIPHENODIOXAZINE-DISULFIMIDE REACTIVE DYES | BAYER AG (DE) | 1989-01-18 | — | — | EP | disclosed |
| EP-0204245-B1 | REACTIVE DYES | BAYER AG (DE) | 1988-12-21 | — | — | EP | disclosed |
| EP-0205080-A2 | Triphenodioxazine-disulfimide reactive dyes | BAYER AG (DE) | 1986-12-17 | — | — | EP | disclosed |
| EP-0204245-A2 | Reactive dyes | BAYER AG (DE) | 1986-12-10 | — | — | EP | disclosed |
| EP-0190603-A2 | Aminoalkylenesulfone-triphenedioxazine dyes | BAYER AG (DE) | 1986-08-13 | — | — | EP | disclosed |