Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | MMP14 | P50281 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 4/20 | 0.45 |
| ▸ | ACE | P12821 | 3/20 | 0.45 |
| ▸ | PYGL | P06737 | 8/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890766 | 1.00 | MMP9 (0.52) | MMP9MMP8MMP14MMEACE | |
| SCHEMBL6898835 | 0.97 | MMP8 (0.51) | MMP9MMP8MMP14MMEACE | |
| SCHEMBL7752057 | 0.97 | MMP8 (0.51) | MMP9MMP8MMP14MMEACE | |
| SCHEMBL7752030 | 0.93 | MMP9 (0.54) | MMP9MMP8MMP14MMEACE | |
| SCHEMBL6897320 | 0.93 | MMP9 (0.54) | MMP9MMP8MMP14MMEACE | |
| SCHEMBL6898216 | 0.86 | MMP9 (0.47) | MMP9MMP8MMP14MMEACE | |
| SCHEMBL7748123 | 0.86 | MMP9 (0.51) | MMP9MMP8MMP14MMEACE | |
| SCHEMBL6895678 | 0.86 | MMP9 (0.51) | MMP9MMP8MMP14MMEACE | |
| SCHEMBL6894662 | 0.86 | MMP9 (0.47) | MMP9MMP8MMP14MMEACE | |
| SCHEMBL6891245 | 0.84 | MMP9 (0.49) | MMP9MMP8MMP14MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1299344-A | Novel urea derivatives | SANTEN PHARCEUMATICAL CO LTD (JP) | 2001-06-13 | — | — | CN | disclosed |
| EP-1072591-A1 | NOVEL UREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-01-31 | — | — | EP | disclosed |