Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7752408 | 0.73 | CYP2C19 (0.45) | CYP2C19ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7753150 | 0.73 | CYP2C19 (0.45) | CYP2C19ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL17866226 | 0.70 | CYP2C19 (0.45) | CYP2C19ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2033382 | 0.69 | CYP2C19 (0.44) | CYP2C19ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2035441 | 0.69 | CYP2C19 (0.46) | CYP2C19ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5854775 | 0.68 | CYP2C19 (0.43) | CYP2C19ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL2033385 | 0.68 | CYP2C19 (0.43) | CYP2C19ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2040601 | 0.68 | CYP2C19 (0.43) | CYP2C19ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5853853 | 0.68 | CYP2C19 (0.43) | CYP2C19ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5854814 | 0.68 | CYP2C19 (0.43) | CYP2C19ALDH1A1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727443-B1 | Catalyst for olefin polymerization and process for producing olefin polymers | TOSOH CORP (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-5807938-A | Catalyst for olefin polymerization and process for producing olefin polymers | TOSOH CORPORATION (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0730003-B1 | Polypropylene resin composition and molded product | TOSOH CORP (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5608008-A | ETHYLENE-A-OLEFIN COPOLYMER ELASTOMER | TOSOH CORPORATION (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0730003-A1 | Polypropylene resin composition and molded product | Tosoh Corporation (JP) | 1996-09-04 | — | — | EP | disclosed |
| EP-0727443-A1 | Catalyst for olefin polymerization and process for producing olefin polymers | Tosoh Corporation (JP) | 1996-08-21 | — | — | EP | disclosed |