Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | CDC42 | P60953 | 1/20 | 0.44 |
| ▸ | RAC1 | P63000 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20232564 | 0.83 | HSD17B10 (0.46) | HSD17B10LDHAAKR1C3AKR1C2PTGS2 | |
| SCHEMBL2484247 | 0.81 | POLB (0.42) | TSHRITGB2ICAM1ITGAL | |
| SCHEMBL31355498 | 0.81 | POLB (0.42) | TSHRITGB2ICAM1ITGAL | |
| SCHEMBL19313248 | 0.80 | GAA (0.53) | HPGDHTR2A | |
| SCHEMBL2422165 | 0.80 | HSD17B10 (0.50) | HSD17B10LDHATSHRHTR2A | |
| SCHEMBL15931768 | 0.80 | FFAR4 (0.41) | ADAM17 | |
| SCHEMBL12713189 | 0.78 | PPARA (0.43) | CYP1A2TSHRHTR2A | |
| SCHEMBL6976171 | 0.78 | ABCB11 (0.44) | HPGDHSD17B10TSHRHTR2A | |
| SCHEMBL2655696 | 0.78 | CA1 (0.47) | HPGDHSD17B10AKR1C3AKR1C2PTGS2 | |
| SCHEMBL7390154 | 0.78 | HTR2A (0.46) | HPGDHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2746301-B1 | Catalyst | BOREALIS AG (AT) | 2018-05-30 | — | — | EP | disclosed |
| EP-2746301-B1 | Catalyst | BOREALIS AG (AT) | 2018-05-30 | — | — | EP | disclosed |
| EP-2729479-B1 | CATALYSTS | BOREALIS AG (AT) | 2017-09-06 | — | — | EP | disclosed |
| EP-2729479-B1 | CATALYSTS | BOREALIS AG (AT) | 2017-09-06 | — | — | EP | disclosed |
| US-9630980-B2 | Asymmetrical ligands | BOREALIS AG (AT) | 2017-04-25 | — | — | US | disclosed |
| US-9630980-B2 | Asymmetrical ligands | BOREALIS AG (AT) | 2017-04-25 | — | — | US | disclosed |
| US-9630980-B2 | Asymmetrical ligands | BOREALIS AG (AT) | 2017-04-25 | — | — | US | disclosed |
| US-9598517-B2 | Catalysts | BOREALIS AG (AT) | 2017-03-21 | — | — | US | disclosed |
| US-9598517-B2 | Catalysts | BOREALIS AG (AT) | 2017-03-21 | — | — | US | disclosed |
| US-9598517-B2 | Catalysts | BOREALIS AG (AT) | 2017-03-21 | — | — | US | disclosed |
| WO-2014096166-A1 | CATALYSTS | BOREALIS AG (AT) | 2014-06-26 | — | — | WO | disclosed |
| WO-2014096166-A1 | CATALYSTS | BOREALIS AG (AT) | 2014-06-26 | — | — | WO | disclosed |
| EP-2746301-A1 | Catalyst | Borealis AG (AT) | 2014-06-25 | — | — | EP | disclosed |
| EP-2746301-A1 | Catalyst | Borealis AG (AT) | 2014-06-25 | — | — | EP | disclosed |
| EP-2729479-A1 | CATALYSTS | Borealis AG (AT) | 2014-05-14 | — | — | EP | disclosed |
| WO-2013007650-A1 | CATALYSTS | BOREALIS AG (AT) | 2013-01-17 | — | — | WO | disclosed |
| WO-2013007650-A1 | CATALYSTS | BOREALIS AG (AT) | 2013-01-17 | — | — | WO | disclosed |
| EP-1070039-A1 | OXIDATION PROCESS USING TEMPO | Merck & Co., Inc. (US) | 2001-01-24 | — | — | EP | disclosed |
| US-6127573-A | CATALYZED OXIDATION OF PRIMARY ALCOHOLS TO CORRESPONDING CARBOXYLIC ACIDS IN THE PRESENCE OF CATALYTIC AMOUNT OF SODIUM CHLORITE AND STOICHIOMETRIC AMOUNT OF SODIUM HYPOCHLORITE AS AN OXIDANT | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |
| WO-1999052849-A1 | OXIDATION PROCESS USING TEMPO | MERCK & CO., INC. (US) | 1999-10-21 | — | — | WO | disclosed |