Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19313248 | 0.86 | GAA (0.53) | HTR2AHPGDGAAHTR1ASLC6A4 | |
| SCHEMBL9171220 | 0.81 | HTR2A (0.70) | HTR2AGAATAAR1ADRA1A | |
| SCHEMBL6976171 | 0.80 | ABCB11 (0.44) | HTR2AHPGDGAAHTR1ASLC6A4 | |
| SCHEMBL1058869 | 0.80 | HTR2A (0.44) | HTR2AHPGDHTR1ASLC6A4TAAR1 | |
| SCHEMBL15882751 | 0.78 | HTR1A (0.43) | HTR2AHTR1ASLC6A4TAAR1ADRA1A | |
| SCHEMBL7753214 | 0.78 | HPGD (0.46) | HTR2AHPGD | |
| SCHEMBL7551792 | 0.77 | ADRA1A (0.48) | HTR2AHTR1ASLC6A4TAAR1ADRA1A | |
| SCHEMBL15376829 | 0.77 | TSHR (0.46) | HTR2AHPGDHTR1ASLC6A4ADRA1A | |
| Bromide SCHEMBL7547135 | 0.77 | HTR2A (0.42) | HTR2AHPGDHTR1ASLC6A4TAAR1 | |
| SCHEMBL2001551 | 0.76 | HSD17B10 (0.44) | HTR2AHPGDHTR1ASLC6A4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070061-A4 | OXIDATION PROCESS USING PERIODIC ACID | MERCK & CO INC (US) | 2001-11-07 | — | — | EP | disclosed |
| EP-1070041-A4 | PHOSPHATE-MEDIATED CYCLIZATION | MERCK & CO INC (US) | 2001-05-16 | — | — | EP | disclosed |
| EP-1070061-A1 | OXIDATION PROCESS USING PERIODIC ACID | Merck & Co., Inc. (US) | 2001-01-24 | — | — | EP | disclosed |
| EP-1070062-A1 | OXIDATION PROCESS USING TEMPO | Merck & Co., Inc. (US) | 2001-01-24 | — | — | EP | disclosed |
| EP-1070041-A1 | PHOSPHATE-MEDIATED CYCLIZATION | Merck & Co., Inc. (a New Jersey corp.) (US) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052899-A1 | OXIDATION PROCESS USING PERIODIC ACID | MERCK & CO., INC. (US) | 1999-10-21 | — | — | WO | disclosed |
| WO-1999052851-A1 | PHOSPHATE-MEDIATED CYCLIZATION | MERCK & CO., INC. (US) | 1999-10-21 | — | — | WO | disclosed |
| WO-1999052900-A1 | OXIDATION PROCESS USING TEMPO | MERCK & CO., INC. (US) | 1999-10-21 | — | — | WO | disclosed |