Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL231822 | 0.96 | GAA (0.40) | GAAKDM4ECCR1SPRPOLB | |
| SCHEMBL29419078 | 0.96 | GAA (0.40) | GAAKDM4ECCR1SPRPOLB | |
| SCHEMBL29419132 | 0.96 | GAA (0.40) | GAAKDM4ECCR1SPRPOLB | |
| SCHEMBL29419093 | 0.96 | GAA (0.40) | GAAKDM4ECCR1SPRPOLB | |
| SCHEMBL169067 | 0.96 | GAA (0.40) | GAAKDM4ECCR1SPRPOLB | |
| SCHEMBL122901 | 0.96 | GAA (0.40) | GAAKDM4ECCR1SPRPOLB | |
| SCHEMBL15049770 | 0.91 | GAA (0.40) | GAAKDM4ECCR1SPRPOLB | |
| SCHEMBL15049769 | 0.91 | GAA (0.40) | GAAKDM4ECCR1SPRPOLB | |
| SCHEMBL774497 | 0.91 | GAA (0.38) | GAAKDM4ECCR1SPRPOLB | |
| SCHEMBL775572 | 0.91 | GAA (0.40) | GAAKDM4ECCR1SPRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586611-B2 | Fungicidal carboxamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-11-19 | — | — | US | claimed |
| EP-1948649-B1 | FUNGICIDAL CARBOXAMIDES | DU PONT (US) | 2013-06-26 | — | — | EP | claimed |
| CN-101228156-B | Fungicidal carboxamides | DU PONT | 2012-07-18 | — | — | CN | claimed |
| US-20120070421-A1 | Synergistic Fungicidal Mixtures | BASF SE (DE) | 2012-03-22 | — | — | US | claimed |
| US-20110269712-A1 | Fungicidal Carboxamides | BISAHA JOHN JOSEPH | 2011-11-03 | — | — | US | claimed |
| US-8586611-B2 | Fungicidal carboxamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-11-19 | — | — | US | disclosed |
| EP-1948649-B1 | FUNGICIDAL CARBOXAMIDES | DU PONT (US) | 2013-06-26 | — | — | EP | disclosed |
| CN-101228156-B | Fungicidal carboxamides | DU PONT | 2012-07-18 | — | — | CN | disclosed |
| EP-2437604-A2 | SYNERGISTIC FUNGICIDAL MIXTURES | BASF SE (DE) | 2012-04-11 | — | — | EP | disclosed |
| US-20120070421-A1 | Synergistic Fungicidal Mixtures | BASF SE (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20110269712-A1 | Fungicidal Carboxamides | BISAHA JOHN JOSEPH | 2011-11-03 | — | — | US | disclosed |
| WO-2010139656-A2 | SYNERGISTIC FUNGICIDAL MIXTURES | BASF SE (DE) | 2010-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269712-A1 | Fungicidal Carboxamides | NAT1, PFAS, CHRM1 | GAA 421/4885KDM4E 1416/4885CCR1 1540/4885 |
| US-20120070421-A1 | Synergistic Fungicidal Mixtures | CYP1A2, CYP51A1, CYP3A7 | GAA 692/4885KDM4E 2278/4885CCR1 2031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.