Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 4/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27448893 | 0.91 | YAP1 (0.56) | YAP1GPR119ITGB3ITGA2BP2RX7 | |
| SCHEMBL7748646 | 0.89 | BCHE (0.51) | YAP1GPR119BCHEACHEITGB3 | |
| SCHEMBL8186293 | 0.89 | YAP1 (0.54) | YAP1GPR119BCHEACHEITGB3 | |
| SCHEMBL8184024 | 0.88 | YAP1 (0.52) | YAP1GPR119BCHEACHEITGB3 | |
| SCHEMBL2999882 | 0.85 | YAP1 (0.62) | YAP1BCHEACHEP2RX7CACNA1F | |
| SCHEMBL8147986 | 0.85 | YAP1 (0.62) | YAP1BCHEACHEP2RX7CACNA1F | |
| SCHEMBL2999886 | 0.85 | YAP1 (0.62) | YAP1BCHEACHEP2RX7CACNA1F | |
| SCHEMBL8176444 | 0.84 | YAP1 (0.49) | YAP1GPR119BCHEACHEITGB3 | |
| SCHEMBL6967652 | 0.84 | BCHE (0.51) | YAP1GPR119BCHEACHEITGB3 | |
| SCHEMBL12249924 | 0.84 | YAP1 (0.62) | YAP1GPR119P2RX7KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-B1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMA (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |