Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.51 |
| ▸ | ACHE | P22303 | 6/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.49 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.48 |
| ▸ | YAP1 | P46937 | 3/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7753390 | 0.89 | YAP1 (0.55) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL6967652 | 0.89 | BCHE (0.51) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL8186293 | 0.88 | YAP1 (0.54) | BCHEACHEGPR119ITGB3ITGA2B | |
| SCHEMBL8184024 | 0.85 | YAP1 (0.52) | BCHEACHEGPR119ITGB3ITGA2B | |
| SCHEMBL27448893 | 0.85 | YAP1 (0.56) | GPR119ITGB3ITGA2BYAP1P2RX7 | |
| SCHEMBL7753201 | 0.84 | MMP13 (0.46) | BCHEACHEGPR119ITGB3ITGA2B | |
| SCHEMBL6970413 | 0.82 | BCHE (0.47) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL7752671 | 0.82 | SYK (0.60) | ITGB3ITGA2BMAPTMAPK1 | |
| SCHEMBL6936056 | 0.81 | ITGB3 (0.69) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL27449336 | 0.79 | YAP1 (0.51) | GPR119YAP1P2RX7MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-B1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMA (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |