Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.56 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 4/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | HPN | P05981 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748703 | 0.97 | ITGB3 (0.55) | ITGB3ITGA2BITGAVMMP2MMP9 | |
| SCHEMBL27489722 | 0.92 | ITGB3 (0.67) | ITGB3ITGA2BITGAVMMP3MMP13 | |
| SCHEMBL7753368 | 0.92 | ITGB3 (0.67) | ITGB3ITGA2BITGAVMMP3MMP13 | |
| SCHEMBL8189053 | 0.90 | MMP2 (0.52) | ITGB3ITGA2BITGAVMMP2MMP9 | |
| SCHEMBL7752535 | 0.89 | ITGB3 (0.66) | ITGB3ITGA2BITGAVMMP3MMP13 | |
| SCHEMBL27547990 | 0.89 | ITGB3 (0.66) | ITGB3ITGA2BITGAVMMP3MMP13 | |
| SCHEMBL7752448 | 0.88 | ITGB3 (0.54) | ITGB3ITGA2BITGAVMMP3MMP13 | |
| SCHEMBL7753569 | 0.88 | ITGB3 (0.55) | ITGB3ITGA2BITGAVMMP2MMP9 | |
| SCHEMBL7752735 | 0.86 | ITGB3 (0.59) | ITGB3ITGA2BITGAVMMP2MMP9 | |
| SCHEMBL7748645 | 0.84 | ITGAV (0.48) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-B1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMA (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |