SCHEMBL7753500

SCHEMBL7753500

CN(C)/C(=C\[N+](=O)[O-])N(C)c1ccc(Cl)nc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.36
MAPT P10636 5/20 0.35
ALDH1A1 P00352 8/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
LMNA P02545 3/20 0.33
NAPRT Q6XQN6 1/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
CYP2D6 P10635 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
HTT P42858 1/20 0.31
CHRNA1 P02708 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA7 P36544 1/20 0.31
JAK2 O60674 1/20 0.31
MITF O75030 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27360047 1.00 SMN1; SMN2 (0.36) SMN1; SMN2MAPTALDH1A1MEN1KMT2A
SCHEMBL7660137 0.88 ALDH1A1 (0.33) SMN1; SMN2MAPTALDH1A1MEN1KMT2A
SCHEMBL14354912 0.83 SMN1; SMN2 (0.33) SMN1; SMN2MAPTALDH1A1MEN1KMT2A
SCHEMBL27300632 0.83 SMN1; SMN2 (0.33) SMN1; SMN2MAPTALDH1A1MEN1KMT2A
SCHEMBL7753213 0.82 MAPT (0.39) SMN1; SMN2MAPTALDH1A1MEN1KMT2A
SCHEMBL10440281 0.82 MAPT (0.39) SMN1; SMN2MAPTALDH1A1MEN1KMT2A
SCHEMBL7752451 0.81 ALDH1A1 (0.34) SMN1; SMN2MAPTALDH1A1MEN1KMT2A
SCHEMBL7658017 0.81 ALDH1A1 (0.34) SMN1; SMN2MAPTALDH1A1MEN1KMT2A
SCHEMBL7672435 0.78 CHRNB2 (0.41) SMN1; SMN2MAPTALDH1A1MEN1KMT2A
SCHEMBL7753165 0.78 CHRNB2 (0.41) SMN1; SMN2MAPTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312204-B2 Insecticides BAYER AKTIENGESELLSCHAFT (DE) 2007-12-25 US disclosed
EP-0632957-B1 A method of killing noxious insects BAYER AGROCHEM KK (JP) 2001-01-17 EP disclosed
US-5882670-A MUSHROOM-CARRYING CRUSHED OR GROUND BROAD LEAVED TREE ATTRACTANT NIHON BAYER AGROCHEM K.K. (JP) 1999-03-16 US disclosed
US-5880142-A SYNERGISTIC MIXTURE OF CYFLUTHRIN AND SPECIFIC PERMEABLE INSECTICIDE NIHON BAYER AGROCHEM K.K. (JP) 1999-03-09 US disclosed
EP-0648412-B1 Poisonous baits for controlling soil-inhabiting pests BAYER AGROCHEM KK (JP) 1998-12-02 EP disclosed
US-5707640-A INSECTICIDES FOR SOILS NIHON BAYER AGROCHEM K.K. (JP) 1998-01-13 US disclosed
US-5661164-A APPLYING A SYNERGISTIC MIXTURE OF CYFLUTHRIN, 1-(6-CHLORO-3-PYRIDYLMETHYL)-N-NITROIMIDAZOLIDIN-2-YLIDENE-AMINE AND A CARRIER NIHON BAYER AGROCHEM K.K. (JP) 1997-08-26 US disclosed
US-5561945-A PRESSURE FORCES ABSORPTION OF ACTIVE MATERIAL INTO STEMS NIHON BAYER AGROCHEM K.K. (JP) 1996-10-08 US disclosed
EP-0366085-B1 Tetrahydropyrimidines, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1996-04-17 EP disclosed
US-5455256-A Controlling thrips NIHON BAYER AGROCHEM K.K. (JP) 1995-10-03 US disclosed
EP-0648412-A1 Poisonous baits for controlling soil-inhabiting pests NIHON BAYER AGROCHEM K.K. (JP) 1995-04-19 EP disclosed
EP-0632957-A1 A method of killing noxious insects NIHON BAYER AGROCHEM K.K. (JP) 1995-01-11 EP disclosed
EP-0617890-A1 Synergistic insecticidal compositions NIHON BAYER AGROCHEM K.K. (JP) 1994-10-05 EP disclosed
EP-0366085-A2 Tetrahydropyrimidines, their production and use Takeda Chemical Industries, Ltd. (JP) 1990-05-02 EP disclosed