SCHEMBL7753537

SCHEMBL7753537

N#CCCCCCNC(N)=O

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
ALDH1A2 O94788 1/20 0.39
ALDH2 P05091 1/20 0.39
ALDH1A3 P47895 1/20 0.39
KDM4E B2RXH2 1/20 0.38
MAPK1 P28482 1/20 0.38
HIF1A Q16665 1/20 0.38
GBA1 P04062 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
PAOX Q6QHF9 2/20 0.36
MCL1 Q07820 1/20 0.34
EPHX1 P07099 3/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
EPHX2 P34913 1/20 0.34
MMP8 P22894 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20220922 0.91
SCHEMBL3967703 0.82
SCHEMBL28560371 0.82 KDM4E (0.52) ALDH1A1ALDH1A2ALDH2ALDH1A3KDM4E
SCHEMBL1837168 0.82 KDM4E (0.52) ALDH1A1ALDH1A2ALDH2ALDH1A3KDM4E
SCHEMBL11180722 0.82 KDM4E (0.52) ALDH1A1ALDH1A2ALDH2ALDH1A3KDM4E
SCHEMBL28622543 0.82 KDM4E (0.52) ALDH1A1ALDH1A2ALDH2ALDH1A3KDM4E
SCHEMBL11173620 0.82 KDM4E (0.52) ALDH1A1ALDH1A2ALDH2ALDH1A3KDM4E
SCHEMBL1839119 0.82 KDM4E (0.52) ALDH1A1ALDH1A2ALDH2ALDH1A3KDM4E
SCHEMBL1309360 0.82 KDM4E (0.52) ALDH1A1ALDH1A2ALDH2ALDH1A3KDM4E
SCHEMBL11082957 0.81 ALDH1A1 (0.40) ALDH1A1ALDH1A2ALDH2ALDH1A3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2001261630-A METHOD FOR PRODUCING CYANOACYLUREA COMPOUNDS MITSUI CHEMICALS INC 2001-09-26 JP disclosed
US-4188401-A Combating fungi with 1-(ω-substituted pentyl)-3-(2-cyano-acetyl)-ureas BAYER AKTIENGESELLSCHAFT (DE) 1980-02-12 US disclosed
US-4182775-A Benzoic acids and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-08 US disclosed