SCHEMBL7753634

SCHEMBL7753634

Nc1nc2ncc(CN(C=O)C3=CCC([C]=O)CC3)nc2c(=O)[nH]1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ NOS1 P29475 13/20 0.44
▸ HSD17B10 Q99714 3/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ HPGD P15428 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ TYMS P04818 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ AKR1B1 P15121 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ PTGS2 P35354 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2509297 0.78 NOS1 (0.46) NOS1HSD17B10KDM4EMEN1ALDH1A1
SCHEMBL3330977 0.70 NOS1 (0.50) NOS1HSD17B10KDM4EMEN1ALDH1A1
SCHEMBL16116814 0.70 NOS1 (0.47) NOS1HSD17B10KDM4EMEN1ALDH1A1
SCHEMBL7757815 0.68 NOS1 (0.43) NOS1HSD17B10KDM4EMEN1ALDH1A1
SCHEMBL12948270 0.67 NOS1 (0.72) NOS1HSD17B10KDM4EMEN1ALDH1A1
SCHEMBL6444228 0.67 NOS1 (0.68) NOS1HSD17B10KDM4EMEN1ALDH1A1
SCHEMBL14791099 0.66 NOS1 (0.69) NOS1HSD17B10KDM4EMEN1ALDH1A1
SCHEMBL1520051 0.65 NOS1 (0.68) NOS1HSD17B10KDM4EMEN1ALDH1A1
SCHEMBL1981720 0.65 NOS1 (0.68) NOS1HSD17B10KDM4EMEN1ALDH1A1
SCHEMBL21204949 0.65 NOS1 (0.68) NOS1HSD17B10KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001056385-A1 METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS NONOMURA ARTHUR M (US) 2001-08-09 — — WO claimed
US-6121195-A STIMULATING CARBON FIXATION AND INCREASING THE GROWTH OF PLANTS BY ENHANCING THE AVAILABILITY OF C1-TETRAHYDROFOLATE IN THE LEAVES OF A PLANT NONOMURA ARTHUR M (US) 2000-09-19 — — US claimed
EP-0813510-A4 METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS NONOMURA ARTHUR M (US) 2000-07-26 — — EP claimed
EP-0813510-A1 METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS NONOMURA, Arthur M. (US) 1997-12-29 — — EP claimed
WO-1996027572-A1 METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS NONOMURA ARTHUR M (US) 1996-09-12 — — WO claimed
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