Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 11/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980437 | 0.83 | AKR1B1 (0.47) | NOS1HSD17B10KDM4EALDH1A1MEN1 | |
| SCHEMBL851772 | 0.81 | NOS1 (0.47) | NOS1HSD17B10KDM4EALDH1A1MEN1 | |
| SCHEMBL7757815 | 0.79 | NOS1 (0.43) | NOS1HSD17B10KDM4EALDH1A1MEN1 | |
| SCHEMBL7753634 | 0.78 | NOS1 (0.44) | NOS1HSD17B10KDM4EALDH1A1MEN1 | |
| SCHEMBL15794397 | 0.77 | NOS1 (0.47) | NOS1HSD17B10KDM4EALDH1A1MEN1 | |
| SCHEMBL2906514 | 0.76 | TYMS (0.62) | NOS1HSD17B10KDM4EALDH1A1MEN1 | |
| SCHEMBL2905540 | 0.75 | AKR1B1 (0.50) | NOS1HSD17B10KDM4EALDH1A1MEN1 | |
| SCHEMBL15531651 | 0.75 | AKR1B1 (0.48) | NOS1HSD17B10KDM4EALDH1A1MEN1 | |
| SCHEMBL15263068 | 0.74 | AKR1B1 (0.49) | NOS1HSD17B10KDM4EALDH1A1MEN1 | |
| SCHEMBL10112077 | 0.71 | NOS1 (0.67) | NOS1HSD17B10KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140309186-A1 | Metabolomics-Based Identification of Disease-Causing Agents | GEORGIA TECH RESEARCH CORPORATION | 2014-10-16 | — | — | US | disclosed |
| US-20110246081-A1 | Metabolomics-Based Identification of Disease-Causing Agents | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-10-06 | — | — | US | disclosed |
| US-7585617-B2 | For liberating and isolating component materials contained in a biological cell and for qualitative detection and quantitative determination of the liberated materials | INSILICO BIOTECHNOLOGY GMBH (DE) | 2009-09-08 | — | — | US | disclosed |
| US-20070298484-A1 | Method and Device for Thermal Conditioning of a Cell | INSILICO BIOTECHNOLOGY GMBH (DE) | 2007-12-27 | — | — | US | disclosed |
| US-20070225203-A1 | Method and Composition for Preventing Multiple Organ Dysfunction Syndrome | N.V. NUTRICIA (NL) | 2007-09-27 | — | — | US | disclosed |
| EP-1670323-A2 | METHOD AND COMPOSITION FOR PREVENTING MULTIPLE ORGAN DYSFUNCTION SYNDROME | N.V. Nutricia (NL) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005027660-A2 | METHOD AND COMPOSITION FOR PREVENTING MULTIPLE ORGAN DYSFUNCTION SYNDROME | N.V. NUTRICIA (NL) | 2005-03-31 | — | — | WO | disclosed |
| US-5153309-A | PROCESS OF MAKING TETRAHYDROPTEROYLPOLY-L-GLUTAMIC ACID DERIVATIVES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1992-10-06 | — | — | US | disclosed |
| WO-1992002241-A1 | A PROCESS OF MAKING TETRAHYDROPTEROYLPOLY-L-GLUTAMIC ACID DERIVATIVES | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) | 1992-02-20 | — | — | WO | disclosed |