Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8641110 | 0.99 | MEN1 (0.54) | MEN1KMT2AALDH1A1HTTKDM4E | |
| SCHEMBL7759676 | 0.90 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1HTTKDM4E | |
| SCHEMBL7758568 | 0.90 | MEN1 (0.64) | MEN1KMT2AALDH1A1HTTKDM4E | |
| Hydrochloric Acid SCHEMBL8637628 | 0.89 | LMNA (0.48) | MEN1KMT2AALDH1A1HTTKDM4E | |
| Hydrochloric Acid SCHEMBL8639585 | 0.89 | MEN1 (0.62) | MEN1KMT2AALDH1A1HTTKDM4E | |
| SCHEMBL7756379 | 0.83 | MEN1 (0.61) | MEN1KMT2AALDH1A1HTTKDM4E | |
| Hydrochloric Acid SCHEMBL8637185 | 0.82 | MEN1 (0.60) | MEN1KMT2AALDH1A1HTTKDM4E | |
| Ninerafaxstat SCHEMBL29793348 | 0.82 | GAA (0.58) | MEN1KMT2AALDH1A1HTTKDM4E | |
| Ninerafaxstat SCHEMBL29793447 | 0.82 | GAA (0.58) | MEN1KMT2AALDH1A1HTTKDM4E | |
| Ninerafaxstat SCHEMBL20584173 | 0.82 | GAA (0.58) | MEN1KMT2AALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847999-B1 | N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-03-21 | — | — | EP | disclosed |