Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 9/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8659554 | 0.99 | ALDH1A1 (0.56) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL7756372 | 0.91 | ALDH1A1 (0.57) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL7758476 | 0.91 | ALDH1A1 (0.59) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL8636327 | 0.90 | ALDH1A1 (0.56) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL8642718 | 0.90 | ALDH1A1 (0.58) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL7756417 | 0.89 | ALDH1A1 (0.59) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL7758568 | 0.89 | MEN1 (0.64) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL7757935 | 0.89 | MEN1 (0.57) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL8639585 | 0.88 | MEN1 (0.62) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL8635524 | 0.88 | ALDH1A1 (0.58) | ALDH1A1HTTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847999-B1 | N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-03-21 | — | — | EP | disclosed |
| EP-0847999-A1 | N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-06-17 | — | — | EP | disclosed |