Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8639815 | 0.99 | MEN1 (0.56) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL7753782 | 0.89 | MEN1 (0.54) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL7757936 | 0.89 | MEN1 (0.54) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL7757485 | 0.89 | MEN1 (0.54) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL7756372 | 0.89 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL7753771 | 0.89 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL7758568 | 0.88 | MEN1 (0.64) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL7758476 | 0.88 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL8638152 | 0.88 | MEN1 (0.53) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL8635529 | 0.88 | MEN1 (0.53) | MEN1KMT2AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847999-B1 | N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-03-21 | — | — | EP | disclosed |
| EP-0847999-A1 | N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-06-17 | — | — | EP | disclosed |