SCHEMBL77538

SCHEMBL77538

COCCOc1ccc(O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.59
NR5A1 Q13285 1/20 0.59
APP P05067 2/20 0.49
MAPT P10636 1/20 0.48
DRD2 P14416 1/20 0.47
DRD4 P21917 1/20 0.47
DRD3 P35462 1/20 0.47
CYP1A2 P05177 2/20 0.47
LMNA P02545 1/20 0.47
PTGS1 P23219 1/20 0.47
SLC6A2 P23975 1/20 0.47
CYP2C19 P33261 1/20 0.47
PTGS2 P35354 1/20 0.47
SLC6A3 Q01959 1/20 0.47
HIF1A Q16665 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
ESR2 Q92731 3/20 0.46
ESR1 P03372 2/20 0.46
CYP19A1 P11511 2/20 0.46
CYP3A4 P08684 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL842057 0.94 APP (0.57) LTA4HNR5A1APPMAPTDRD2
SCHEMBL1478767 0.94 APP (0.57) LTA4HNR5A1APPMAPTDRD2
SCHEMBL16305613 0.94 APP (0.57) LTA4HNR5A1APPMAPTDRD2
SCHEMBL7917011 0.94 ESR2 (0.57) LTA4HNR5A1APPMAPTDRD2
SCHEMBL12264007 0.90 PTPN1 (0.57) LTA4HNR5A1APPDRD4CYP1A2
SCHEMBL10879381 0.89 LTA4H (0.62) LTA4HNR5A1APPDRD2DRD4
SCHEMBL11601640 0.89 NR5A1 (0.68) LTA4HNR5A1APPDRD2DRD4
SCHEMBL16305604 0.89 APP (0.53) LTA4HNR5A1APPESR2
SCHEMBL226548 0.88 LTA4H (0.64) LTA4HNR5A1APPDRD2DRD4
SCHEMBL8339774 0.88 MAPT (0.52) LTA4HMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109724-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES INC (US) 2026-04-23 US disclosed
EP-4107164-B1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES INC (US) 2025-12-03 EP disclosed
EP-4539840-A1 KINASE MODULATORS AND METHODS OF USE THEREOF Neuron23, Inc. (US) 2025-04-23 EP disclosed
US-12264173-B2 Antiviral compounds GILEAD SCIENCES, INC. (US) 2025-04-01 US disclosed
CN-119730846-A Kinase modulators and methods of use thereof 神经元23公司 2025-03-28 CN disclosed
US-20250026749-A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS GENZYME CORPORATION (US) 2025-01-23 US disclosed
WO-2023244788-A9 KINASE MODULATORS AND METHODS OF USE THEREOF NEURON23, INC. (US) 2024-09-12 WO disclosed
US-12060349-B2 Glucosylceramide synthase inhibitors GENZYME CORPORATION (US) 2024-08-13 US disclosed
US-20240174704-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2024-05-30 US disclosed
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF SUNDANCE BIOSCIENCES, INC. 2024-01-25 US disclosed
US-4816604-A CARDIOVASCULAR DISORDERS Louis, William J. (AU) 1989-03-28 US disclosed
WO-1989000849-A1 CELL GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES BAYLOR COLLEGE OF MEDICINE (US) 1989-02-09 WO disclosed
US-4636501-A ADRENERGIC BETA BLOCKERS AKTIEBOLAGET HASSLE (SE) 1987-01-13 US disclosed
EP-0085286-B1 PARA-SUBSTITUTED 3-PHENOXY-1-CARBONYLAMINOALKYLAMINO-PROPAN-2-OLS HAVING BETA RECEPTOR BLOCKING PROPERTIES Aktiebolaget Hässle (SE) 1986-04-30 EP disclosed
EP-0083839-B1 PROCESS FOR PRODUCING INORGANIC FIBER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-03-05 EP disclosed
EP-0052072-B1 3-AMINOPROPOXYPHENYL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SANDOZ AG (CH) 1985-02-20 EP disclosed
US-4495121-A SPINNING A POLYMETALOXANE, CALCINING SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1985-01-22 US disclosed
US-4425362-A CARDIOVASCULAR DISORDERS, ADRENERGIC BLOCKING AGENTS SANDOZ LTD. (CH) 1984-01-10 US disclosed
EP-0085286-A1 Para-substituted 3-phenoxy-1-carbonylaminoalkylamino-propan-2-ols having beta receptor blocking properties Aktiebolaget Hässle (SE) 1983-08-10 EP disclosed
US-3949088-A Substituted phenoxy propanol amines used for treating cardiovascular diseases SAMUELSSON BENNY ROGER 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109724-A1 ANTIVIRAL COMPOUNDS IRF3, IFNAR1, HAVCR2 LTA4H 1754/4885NR5A1 523/4885APP 4605/4885
US-12264173-B2 Antiviral compounds MAVS, HAVCR2, ZC3HAV1 LTA4H 846/4885NR5A1 3862/4885APP 3938/4885
US-12060349-B2 Glucosylceramide synthase inhibitors GBA1, GBA2, GALC LTA4H 433/4885NR5A1 3146/4885APP 3516/4885
US-20250026749-A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS GBA1, GBA2, GAA LTA4H 299/4885NR5A1 4154/4885APP 3148/4885
US-20240174704-A1 ANTIVIRAL COMPOUNDS MAVS, HAVCR2, ZC3HAV1 LTA4H 846/4885NR5A1 3862/4885APP 3938/4885
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF TYK2, JAK1, JAK3 LTA4H 2979/4885NR5A1 4276/4885APP 4374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.