Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18735901 | 1.00 | MGAM (0.40) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL18736159 | 1.00 | MGAM (0.40) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL18735985 | 0.82 | ALOX15 (0.56) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL18736150 | 0.82 | ALOX15 (0.56) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL12446349 | 0.82 | ALOX15 (0.56) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL10334455 | 0.81 | TSHR (0.36) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL10334453 | 0.81 | TSHR (0.36) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL5571591 | 0.81 | MGAM (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL28055033 | 0.81 | CYP1A2 (0.46) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL5001444 | 0.80 | MGAM (0.46) | MGAMGAASIMGAM2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017062468-A1 | PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | MITOBRIDGE, INC. (US) | 2017-04-13 | — | — | WO | disclosed |
| WO-2001046115-A1 | UNSATURATED FATTY ACIDS AND THEIR USES IN THERAPY | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2001-06-28 | — | — | WO | disclosed |