Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ADH1B | P00325 | 3/20 | 0.36 |
| ▸ | ADH1A | P07327 | 3/20 | 0.36 |
| ▸ | ADH7 | P40394 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21866139 | 0.83 | GAA (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL5567613 | 0.83 | MGAM (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL18735901 | 0.81 | MGAM (0.40) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL18736159 | 0.81 | MGAM (0.40) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL25873789 | 0.81 | GAA (0.45) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL7753856 | 0.81 | MGAM (0.40) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL7420530 | 0.77 | SLC15A1 (0.46) | ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL6036647 | 0.77 | BHMT (0.40) | ALDH1A1ADH1BADH1AADH7ADH1C | |
| SCHEMBL7952798 | 0.76 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL5001444 | 0.76 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819693-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006057868-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |