⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752930 | 0.89 | MAPT (0.52) | — | |
| SCHEMBL7753302 | 0.85 | — | — | |
| SCHEMBL7753893 | 0.83 | ABCB1 (0.55) | — | |
| SCHEMBL7755346 | 0.80 | — | — | |
| SCHEMBL7753930 | 0.73 | MAPT (0.50) | — | |
| SCHEMBL7752942 | 0.70 | — | — | |
| SCHEMBL7752920 | 0.70 | — | — | |
| SCHEMBL7752953 | 0.67 | PIN1 (0.56) | — | |
| SCHEMBL7754198 | 0.67 | — | — | |
| SCHEMBL7753317 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068176-A1 | CYSTEINE AMIDES AS FARNESYL TRANSFERASE INHIBITORS | Jomaa, Hassan (DE) | 2001-01-17 | — | — | EP | disclosed |
| WO-2000027803-A1 | CYSTEINE AMIDES AS FARNESYL TRANSFERASE INHIBITORS | JOMAA, HASSAN (DE) | 2000-05-18 | — | — | WO | disclosed |