Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656404 | 0.86 | NPSR1 (0.50) | NPSR1KDM4EMAPTPOLBMAPK1 | |
| SCHEMBL3340975 | 0.85 | NPSR1 (0.52) | NPSR1KDM4EMAPTPOLBMAPK1 | |
| SCHEMBL4659390 | 0.78 | POLB (0.49) | NPSR1KDM4EMAPTPOLBMAPK1 | |
| SCHEMBL1625289 | 0.77 | MAPT (0.52) | NPSR1KDM4EMAPTPOLBMAPK1 | |
| SCHEMBL7762950 | 0.77 | NPSR1 (0.46) | NPSR1KDM4EMAPTPOLBMAPK1 | |
| SCHEMBL4658268 | 0.76 | LMNA (0.48) | NPSR1KDM4EMAPTPOLBMAPK1 | |
| SCHEMBL4657836 | 0.75 | KMT2A (0.49) | NPSR1KDM4EMAPTPOLBMAPK1 | |
| SCHEMBL2595990 | 0.74 | MAPT (0.49) | NPSR1KDM4EMAPTPOLBMAPK1 | |
| SCHEMBL11009313 | 0.74 | ALDH1A1 (0.50) | NPSR1KDM4EMAPTPOLBMAPK1 | |
| SCHEMBL17742882 | 0.74 | ALDH1A1 (0.54) | KDM4EMAPTMAPK1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559687-B1 | 2-AMINOCINNAMIC ACID ESTERS | BASF AG (DE) | 2001-01-24 | — | — | EP | disclosed |
| US-5324843-A | Process for making 3,4,5,6-tetrahydrophthalimide derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1994-06-28 | — | — | US | disclosed |