Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132197 | 0.86 | GAA (0.62) | TDP1LMNAMAPTRXFP1POLB | |
| SCHEMBL29772937 | 0.86 | GAA (0.62) | TDP1LMNAMAPTRXFP1POLB | |
| SCHEMBL30853148 | 0.84 | TDP1 (0.57) | TDP1ALDH1A1RXFP1POLBL3MBTL1 | |
| SCHEMBL21050613 | 0.84 | TDP1 (0.57) | TDP1ALDH1A1RXFP1POLBL3MBTL1 | |
| SCHEMBL5674663 | 0.82 | HSD17B10 (0.59) | LMNAMAPTALDH1A1POLBEPHX2 | |
| SCHEMBL31198183 | 0.82 | HSD17B10 (0.59) | LMNAMAPTALDH1A1POLBEPHX2 | |
| SCHEMBL22200937 | 0.81 | TDP1 (0.54) | TDP1LMNAMAPTALDH1A1RXFP1 | |
| SCHEMBL15782653 | 0.81 | TDP1 (0.54) | TDP1MAPTALDH1A1RXFP1POLB | |
| SCHEMBL10864160 | 0.81 | POLB (0.55) | TDP1LMNAMAPTALDH1A1RXFP1 | |
| SCHEMBL13921948 | 0.81 | DHODH (0.51) | TDP1LMNAMAPTALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704539-B1 | Chemiluminescent reagent and assay using a substituted acetanilide for light generation | JOHNSON & JOHNSON CLIN DIAG (US) | 2001-02-28 | — | — | EP | disclosed |
| EP-0603954-B1 | Immunoassay using a 4-hydroxy or 4-alkoxyarylacetamide as stabilizer | JOHNSON & JOHNSON CLIN DIAG (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0603953-B1 | Use of 4' of 5'-hydroxy and 4'- or 5'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods | JOHNSON & JOHNSON CLIN DIAG (US) | 1999-02-17 | — | — | EP | disclosed |
| US-5736335-A | Dry elements, test devices, test kits and methods for chemiluminescent detection of analytes using peroxidase-labeled reagents | EASTMAN KODAK COMPANY (US) | 1998-04-07 | — | — | US | disclosed |
| US-5705357-A | DETECTING PEROXIDASE; SENSITIVITY, LOW BACKGROUND; MEDICAL DIAGNOSIS | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1998-01-06 | — | — | US | disclosed |
| US-5641635-A | Dry elements, test devices, test kits and methods for chemiluminescent detection of analytes using peroxidase-labeled reagents | EASTMAN KODAK COMPANY (US) | 1997-06-24 | — | — | US | disclosed |
| EP-0704539-A2 | Chemiluminescent reagent and assay using a substituted acetanilide for light generation | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1996-04-03 | — | — | EP | disclosed |
| US-5372931-A | Use of 4'-hydroxy- and 4'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods | EASTMAN KODAK COMPANY (US) | 1994-12-13 | — | — | US | disclosed |
| US-5372932-A | Peroxidase-labeled immunoreactant; stabiliztion with a 4-hydroxy or 4-alkoxyarylacetamide | EASTMAN KODAK COMPANY (US) | 1994-12-13 | — | — | US | disclosed |
| EP-0603953-A1 | Use of 4' of 5'-hydroxy and 4'- or 5'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1994-06-29 | — | — | EP | disclosed |
| EP-0603954-A2 | Analytical element and immunoassay using a 4-hydroxy or 4-alkoxyarylacetamide as stabilizer | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1994-06-29 | — | — | EP | disclosed |