SCHEMBL5674663

SCHEMBL5674663

CC(=O)Nc1ccc(O)c(Cl)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 2/20 0.59
▸ ALDH1A1 P00352 5/20 0.58
▸ MAPT P10636 3/20 0.58
▸ LMNA P02545 1/20 0.58
▸ RORC P51449 4/20 0.57
▸ SMN1; SMN2 Q16637 2/20 0.55
▸ ESRRA P11474 1/20 0.55
▸ PKM P14618 1/20 0.54
▸ MEN1 O00255 2/20 0.53
▸ KMT2A Q03164 2/20 0.53
▸ CA12 O43570 1/20 0.53
▸ BRD4 O60885 1/20 0.53
▸ NR1I2 O75469 1/20 0.53
▸ CA1 P00915 1/20 0.53
▸ CA2 P00918 1/20 0.53
▸ MB P02144 1/20 0.53
▸ CYP1A1 P04798 1/20 0.53
▸ CA3 P07451 1/20 0.53
▸ CYP3A4 P08684 1/20 0.53
▸ RARG P13631 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31198183 1.00 HSD17B10 (0.59) HSD17B10ALDH1A1MAPTLMNARORC
SCHEMBL9658038 0.85 ESRRA (0.53) HSD17B10ALDH1A1MAPTLMNARORC
SCHEMBL9815484 0.85 PKM (0.59) ALDH1A1MAPTRORCSMN1; SMN2ESRRA
SCHEMBL4548035 0.84 EPHX1 (0.70) MAPTLMNARORCSMN1; SMN2PKM
SCHEMBL4683057 0.82 MAPT (0.55) HSD17B10ALDH1A1MAPTLMNAPKM
SCHEMBL7754176 0.82 TDP1 (0.53) HSD17B10ALDH1A1MAPTLMNASMN1; SMN2
SCHEMBL3192352 0.82 PKM (0.65) HSD17B10ALDH1A1MAPTLMNASMN1; SMN2
SCHEMBL11357914 0.81 ALDH1A1 (0.59) HSD17B10ALDH1A1MAPTLMNASMN1; SMN2
SCHEMBL7545188 0.81 MAPT (0.63) ALDH1A1MAPTLMNASMN1; SMN2CYP3A4
SCHEMBL3786387 0.81 CA1 (0.58) ALDH1A1MAPTRORCSMN1; SMN2ESRRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240115522-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING PARACETAMOL DERIVATIVES AND USE THEREOF M/S Status Projects Private Limited (IN) 2024-04-11 — — US claimed
CN-108387652-B Method for detecting impurities in compound paracetamol diphenhydramine tablets 四川省食品药品检验检测院 2021-03-02 — — CN claimed
CN-101221170-B Efficient enzymatic chemiluminescent substrate system Shenzhen huaying biotechnology co ltd 2012-04-25 — — CN claimed
CN-101221170-A High-efficiency enzyme promoted chemiluminescence substrate system SHENZHEN HUAYING BIOTECHNOLOGY (CN) 2008-07-16 — — CN claimed
EP-0704539-B1 Chemiluminescent reagent and assay using a substituted acetanilide for light generation JOHNSON & JOHNSON CLIN DIAG (US) 2001-02-28 — — EP claimed
US-5736335-A Dry elements, test devices, test kits and methods for chemiluminescent detection of analytes using peroxidase-labeled reagents EASTMAN KODAK COMPANY (US) 1998-04-07 — — US claimed
US-5705357-A DETECTING PEROXIDASE; SENSITIVITY, LOW BACKGROUND; MEDICAL DIAGNOSIS JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1998-01-06 — — US claimed
US-5641635-A Dry elements, test devices, test kits and methods for chemiluminescent detection of analytes using peroxidase-labeled reagents EASTMAN KODAK COMPANY (US) 1997-06-24 — — US claimed
EP-0704539-A2 Chemiluminescent reagent and assay using a substituted acetanilide for light generation JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1996-04-03 — — EP claimed
US-5372932-A Peroxidase-labeled immunoreactant; stabiliztion with a 4-hydroxy or 4-alkoxyarylacetamide EASTMAN KODAK COMPANY (US) 1994-12-13 — — US claimed
EP-0299891-B1 PROCESS FOR THE SELECTIVE CHLORINATION OF PHENOLIC COMPOUNDS RHONE-POULENC CHIMIE (FR) 1991-12-11 — — EP claimed
US-4999457-A Process for the synthesis of 3-chloro-4-hydroxyacetanilide HOECHST CELANESE CORPORATION (US) 1991-03-12 — — US claimed
EP-0328343-A2 Process for the synthesis of 3-chloro-4-hydroxyacetanilide HOECHST CELANESE CORPORATION (US) 1989-08-16 — — EP claimed
JP-9107991-A — — None — — JP disclosed
JP-8173191-A — — None — — JP disclosed
CN-122010760-A Paracetamol disinfection by-product and preparation method and application thereof 辽宁大学 2026-05-12 — — CN disclosed
EP-0328343-A2 Process for the synthesis of 3-chloro-4-hydroxyacetanilide HOECHST CELANESE CORPORATION (US) 1989-08-16 — — EP disclosed
US-4855499-A Novel process to prevent formation of chlorinated by-products in APAP production HOECHST CELANESE CORPORATION (US) 1989-08-08 — — US disclosed
US-4826987-A Pyridyl and quinoline derivatives LEO PHARMACEUTICAL PRODUCTS LTD. (DK) 1989-05-02 — — US disclosed
US-4279838-A HYDROLYZING AN N-ACETYLAMINOARYL THIOPHOSPHATE OR PHOSPHATE MITSUI TOATSU CHEMICALS INC. (JP) 1981-07-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240115522-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING PARACETAMOL DERIVATIVES AND USE THEREOF PYGL, CYP3A43, CYP3A7 HSD17B10 159/4885ALDH1A1 151/4885MAPT 1184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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