Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5146452 | 0.81 | PRMT5 (0.48) | POLBPRMT5WDR77ADRB3ALDH1A1 | |
| SCHEMBL5141951 | 0.77 | DRD2 (0.60) | POLBPRMT5WDR77ALDH1A1DRD2 | |
| SCHEMBL5143855 | 0.77 | PRMT5 (0.47) | POLBPRMT5WDR77ADRB3ALDH1A1 | |
| SCHEMBL5143959 | 0.76 | ALDH1A1 (0.48) | POLBPRMT5WDR77ADRB3ALDH1A1 | |
| SCHEMBL5143652 | 0.76 | ALDH1A1 (0.48) | POLBPRMT5WDR77ADRB3ALDH1A1 | |
| SCHEMBL7570285 | 0.76 | NPSR1 (0.48) | POLBPRMT5WDR77ADRB3DRD2 | |
| Hydrochloric Acid SCHEMBL5145557 | 0.75 | DRD2 (0.52) | POLBPRMT5WDR77ALDH1A1DRD2 | |
| SCHEMBL5144057 | 0.74 | DRD2 (0.48) | POLBPRMT5WDR77ADRB3ALDH1A1 | |
| SCHEMBL5146546 | 0.74 | PRMT5 (0.46) | POLBPRMT5WDR77ADRB3ALDH1A1 | |
| SCHEMBL5146499 | 0.74 | PRMT5 (0.48) | POLBPRMT5WDR77ADRB3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070046-A1 | PROPANOLAMINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999051564-A1 | PROPANOLAMINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-14 | — | — | WO | disclosed |