Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.49 |
| ▸ | RXRB | P28702 | 14/20 | 0.49 |
| ▸ | RXRG | P48443 | 12/20 | 0.49 |
| ▸ | RARG | P13631 | 7/20 | 0.49 |
| ▸ | RARB | P10826 | 6/20 | 0.49 |
| ▸ | RARA | P10276 | 5/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786489 | 0.85 | RXRA (0.56) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7790860 | 0.85 | RXRA (0.52) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7756218 | 0.78 | RXRA (0.49) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7751874 | 0.78 | RXRA (0.46) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7751742 | 0.74 | RXRA (0.48) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7757696 | 0.73 | RXRA (0.48) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7751877 | 0.72 | CYP3A4 (0.38) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL1073645 | 0.71 | RXRA (0.70) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7790869 | 0.71 | RXRA (0.54) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7790868 | 0.71 | RXRA (0.54) | RXRARXRBRXRGRARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010037025-A1 | New compounds, their preparation and use | MURRAY ANTHONY (DK) | 2001-11-01 | — | — | US | claimed |
| EP-1077919-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-02-28 | — | — | EP | claimed |
| WO-1999058486-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-11-18 | — | — | WO | claimed |
| US-20010037025-A1 | New compounds, their preparation and use | MURRAY ANTHONY (DK) | 2001-11-01 | — | — | US | disclosed |
| EP-1077919-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058486-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010037025-A1 | New compounds, their preparation and use | GPR119, SLC5A1, SLC5A2 | RXRA 874/4885RXRB 1018/4885RXRG 1046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.