SCHEMBL7754586

SCHEMBL7754586

Nc1ccc(N)c(OC(=O)O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.48
TDP1 Q9NUW8 5/20 0.48
KMT2A Q03164 4/20 0.48
THRB P10828 3/20 0.48
RECQL P46063 3/20 0.48
MEN1 O00255 2/20 0.48
POLB P06746 2/20 0.48
USP2 O75604 1/20 0.48
PKM P14618 1/20 0.48
APEX1 P27695 1/20 0.48
BLM P54132 1/20 0.48
MCL1 Q07820 1/20 0.48
ALDH1A1 P00352 8/20 0.47
CYP3A4 P08684 6/20 0.39
KDM4E B2RXH2 5/20 0.39
ALOX15 P16050 3/20 0.39
HSD17B10 Q99714 3/20 0.39
GAA P10253 3/20 0.39
KDR P35968 2/20 0.39
HPGD P15428 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10706035 0.93 MAPT (0.43) MAPTTDP1KMT2ATHRBRECQL
SCHEMBL1551321 0.85 ALDH1A1 (0.48) MAPTTDP1KMT2ATHRBRECQL
SCHEMBL11202193 0.83 ALDH1A1 (0.53) MAPTTDP1KMT2ATHRBRECQL
SCHEMBL1954453 0.83 ALDH1A1 (0.52) MAPTTDP1KMT2ATHRBRECQL
SCHEMBL376800 0.83 ALDH1A1 (0.52) MAPTTDP1KMT2ATHRBRECQL
SCHEMBL7758544 0.83 MAPT (0.44) MAPTTDP1KMT2ATHRBRECQL
SCHEMBL1551903 0.82 KDM4E (0.44) MAPTTDP1KMT2ATHRBRECQL
SCHEMBL26944947 0.82 ALDH1A1 (0.46) MAPTTDP1KMT2ATHRBRECQL
SCHEMBL13929946 0.80 TPMT (0.34) MAPTTDP1KMT2ATHRBRECQL
SCHEMBL28320252 0.80 MAPT (0.51) MAPTTDP1KMT2ATHRBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0774493-B1 Fiber-reactive azo dyestuffs, process for their preparation and use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-04-04 EP disclosed
EP-0735113-B1 Mixtures of reactive dyes and their use CIBA SC HOLDING AG (CH) 2000-10-18 EP disclosed
EP-0627471-B1 Reactive dyes BAYER AG (DE) 2000-08-23 EP disclosed
EP-0309406-B2 Reactive dyes, their preparation and their use CIBA SC HOLDING AG (CH) 2000-07-12 EP disclosed
EP-0652262-B1 Reactive dyestuffs, their preparation and use BAYER AG (DE) 2000-07-12 EP disclosed
EP-0838504-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-06-07 EP disclosed
EP-0962501-A2 Mixtures of reactive dyes and their use for dyeing material containing hydroxy and/or carbonamide groups DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1999-12-08 EP disclosed
EP-0641838-B1 Reactive dye-stuffs on basis of a substituted barbituric acid BAYER AG (DE) 1999-11-10 EP disclosed
EP-0848042-A2 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-06-17 EP disclosed
EP-0838504-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-04-29 EP disclosed
EP-0133843-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-03-06 EP disclosed
EP-0132223-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-01-23 EP disclosed
EP-0131545-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-01-16 EP disclosed
EP-0131542-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-01-16 EP disclosed
EP-0120807-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1984-10-03 EP disclosed
EP-0114032-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1984-07-25 EP disclosed
EP-0105027-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1984-04-04 EP disclosed
EP-0097119-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1983-12-28 EP disclosed
EP-0096659-A2 Process for dyeing or printing fibrous textile materials with reactive dyes CIBA-GEIGY AG (CH) 1983-12-21 EP disclosed
EP-0089923-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1983-09-28 EP disclosed