SCHEMBL28320252

SCHEMBL28320252

Nc1ccc(N)c(OC(=O)c2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.51
KMT2A Q03164 5/20 0.51
SMN1; SMN2 Q16637 4/20 0.51
TSHR P16473 2/20 0.48
ESR1 P03372 2/20 0.47
ESR2 Q92731 2/20 0.47
SLC6A3 Q01959 2/20 0.46
MEN1 O00255 4/20 0.45
USP2 O75604 2/20 0.45
JAK2 O60674 1/20 0.45
GAA P10253 1/20 0.45
ALOX15 P16050 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
HSD17B10 Q99714 1/20 0.45
TDP1 Q9NUW8 2/20 0.45
PARP10 Q53GL7 1/20 0.45
PBRM1 Q86U86 1/20 0.44
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
LMNA P02545 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27639137 0.86 KMT2A (0.51) MAPTKMT2ASMN1; SMN2TSHRESR1
SCHEMBL13915600 0.82 HPGD (0.55) MAPTKMT2ASMN1; SMN2TSHRSLC6A3
SCHEMBL31119217 0.82 KMT2A (0.63) MAPTKMT2ASMN1; SMN2TSHRESR1
SCHEMBL6170616 0.82 KMT2A (0.63) MAPTKMT2ASMN1; SMN2TSHRESR1
SCHEMBL4343990 0.80 KMT2A (0.49) MAPTKMT2ASMN1; SMN2ESR1ESR2
SCHEMBL5058312 0.80 ESR2 (0.56) MAPTKMT2ASMN1; SMN2ESR1ESR2
SCHEMBL2691568 0.80 MAPT (0.51) MAPTKMT2ASMN1; SMN2TSHRESR1
SCHEMBL9153775 0.80 ESR1 (0.46) MAPTKMT2ASMN1; SMN2TSHRESR1
SCHEMBL7754586 0.80 MAPT (0.48) MAPTKMT2ASMN1; SMN2TSHRESR2
SCHEMBL27770400 0.79 KMT2A (0.57) MAPTKMT2ASMN1; SMN2TSHRESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110249004-B Polyimide precursor composition 东京应化工业株式会社 2022-07-19 CN disclosed
CN-110249004-A Polyimide precursor composition 东京应化工业株式会社 2019-09-17 CN disclosed