SCHEMBL7754587

SCHEMBL7754587

O=C(O)C(C(=O)O)c1ccc(O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.64
ALDH1A1 P00352 2/20 0.48
KMT2A Q03164 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
GAA P10253 1/20 0.48
ESR1 P03372 7/20 0.46
ESR2 Q92731 6/20 0.46
CA2 P00918 3/20 0.46
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA3 P07451 2/20 0.46
TYR P14679 2/20 0.46
CA4 P22748 2/20 0.46
CA5A P35218 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CA5B Q9Y2D0 2/20 0.46
DRD1 P21728 2/20 0.46
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL271988 0.89 SRC (0.78) SRCALDH1A1KMT2ATDP1ESR1
SCHEMBL8126795 0.88 SRC (0.50) SRCALDH1A1KMT2ATDP1GAA
SCHEMBL8126791 0.86 SRC (0.48) SRCALDH1A1KMT2ATDP1GAA
SCHEMBL29182115 0.86 SRC (0.48) SRCALDH1A1KMT2ATDP1GAA
SCHEMBL9986143 0.81 SRC (0.67) SRCGAALMNAPKMCYP1A2
SCHEMBL7585373 0.80 CA2 (0.53) SRCALDH1A1KMT2ATDP1GAA
SCHEMBL9701361 0.79 CYP2D6 (0.64) SRCALDH1A1KMT2ATDP1GAA
SCHEMBL180939 0.79 SRC (0.54) SRCALDH1A1KMT2ATDP1GAA
SCHEMBL5597741 0.79 ESR1 (0.46) SRCALDH1A1KMT2ATDP1GAA
SCHEMBL70165 0.78 SRC (1.00) SRCALDH1A1KMT2ATDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4517060-A ALKALI OR AMMONIUM DICYANOAURATE, ALKALI COPPER CYANIDE, BISMUTH COMPLEX SCHERING AKTIENGESELLSCHAFT (DE) 1985-05-14 US claimed
EP-0061219-A1 p-Hydroxyphenylmalonic acid derivatives and process for their preparation Océ-Andeno B.V. (NL) 1982-09-29 EP claimed
WO-2020206381-A1 CEPHEM COMPOUNDS WITH LATENT REACTIVE GROUPS AND METHODS OF USING AND MAKING SAME SUTTON LARRY D (US) 2020-10-08 WO disclosed
WO-2019070973-A1 CEPHEM COMPOUNDS WITH LATENT REACTIVE GROUPS GLADIUS PHARMACEUTICALS CORPORATION (CA) 2019-04-11 WO disclosed
US-20190100534-A1 Cephem Compounds with Latent Reactive Groups GLADIUS PHARMACEUTICALS INC (CA) 2019-04-04 US disclosed
CN-101076457-B Pneumatic tire BRIDGESTONE CORP 2011-07-27 CN disclosed
CN-101076457-A Pneumatic tire BRIDGESTONE CORP (JP) 2007-11-21 CN disclosed
CN-1325595-C Adhesive film, lead frame with adhesive film, and semiconductor device using same HITACHI CHEMICAL CO LTD (JP) 2007-07-11 CN disclosed
CN-1696233-A Adhesive film, lead frame with adhesive film, and semiconductor device using same HITACHI CHEMICAL CO LTD (JP) 2005-11-16 CN disclosed
EP-0716338-B1 Fine polymer particles having heterogeneous phase structure, silver halide photographic light- sensitive material containing the fine polymer particles and image-forming method FUJI PHOTO FILM CO LTD (JP) 2001-10-04 EP disclosed
EP-1100785-A1 SUBSTITUTED CYCLOHEXYLAMINOPYRIMIDINES Aventis CropScience GmbH (DE) 2001-05-23 EP disclosed
EP-0061219-A1 p-Hydroxyphenylmalonic acid derivatives and process for their preparation Océ-Andeno B.V. (NL) 1982-09-29 EP disclosed
EP-0061219-A1 p-Hydroxyphenylmalonic acid derivatives and process for their preparation Océ-Andeno B.V. (NL) 1982-09-29 EP disclosed
EP-0032374-A1 Process for the preparation of p-hydroxyphenylacetic acid HOECHST AKTIENGESELLSCHAFT (DE) 1981-07-22 EP disclosed
US-4273773-A IN COMBINATION WITH A DIURETIC AMERICAN HOME PRODUCTS CORPORATION (US) 1981-06-16 US disclosed
US-4244885-A α-Substituted-3-(halomethyl)-4-hydroxybenzeneacetic acids YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1981-01-13 US disclosed
US-4236002-A ANTIBIOTICS YEDA RESEARCH & DEVELOPMENT CO., LTD. (IL) 1980-11-25 US disclosed
US-4229363-A INTERMEDIATES FOR CEPHALOSPORIN AND PENICILLIN DERIVATIVES YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1980-10-21 US disclosed
US-4198406-A Carbamoyl heterocyclicthio cephalosporins and pharmaceutical compositions formulated therewith BEECHAM GROUP LIMITED (GB) 1980-04-15 US disclosed
US-4197240-A ANTIBIOTICS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1980-04-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190100534-A1 Cephem Compounds with Latent Reactive Groups PGLS, GNE, COMT SRC 3751/4885ALDH1A1 1680/4885KMT2A 1073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.