Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27654260 | 0.88 | HPRT1 (0.52) | HTR1BALDH1A1HSD17B10PGRGAA | |
| SCHEMBL24119672 | 0.86 | ALDH1A1 (0.36) | ALDH1A1HSD17B10GAAKDM4EHPGD | |
| SCHEMBL2681964 | 0.82 | HTR1B (0.48) | HTR1BALDH1A1HSD17B10PGRGAA | |
| SCHEMBL7237089 | 0.80 | HTR1B (0.46) | HTR1BHTR1DSLC6A4HRH1KCNA3 | |
| SCHEMBL17977220 | 0.80 | ALDH1A1 (0.47) | HTR1BALDH1A1HSD17B10PGRGAA | |
| SCHEMBL3884308 | 0.79 | HTR1B (0.43) | HTR1BALDH1A1HSD17B10PGRGAA | |
| SCHEMBL6825603 | 0.79 | MAPT (0.62) | ALDH1A1HSD17B10GAAKDM4EHPGD | |
| SCHEMBL19547983 | 0.79 | HTR1B (0.40) | HTR1BALDH1A1HSD17B10PGRGAA | |
| SCHEMBL7762993 | 0.78 | ALDH1A1 (0.47) | HTR1BALDH1A1HSD17B10PGRGAA | |
| SCHEMBL28862628 | 0.78 | ALDH1A1 (0.39) | HTR1BALDH1A1HSD17B10PGRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104955874-A | Polymerization method and polymers formed therewith | SCRIPPS RESEARCH INST | 2015-09-30 | — | — | CN | disclosed |
| CN-1298379-A | Process for preparing 4-(substituted phenyl)-3.4-dihydro-2H-Naphthalen-1-ones | CIBA SC HOLDING AG (CH) | 2001-06-06 | — | — | CN | disclosed |
| EP-1073617-A1 | PROCESS FOR PREPARING 4-(SUBSTITUTED PHENYL)-3,4-DIHYDRO-2H-NAPHTHALEN-1-ONES | Ciba SC Holding AG (CH) | 2001-02-07 | — | — | EP | disclosed |
| US-6103938-A | Process for preparing 4-(substituted phenyl)-3,4-dihydro-2H-naphthalen-1-ones | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-08-15 | — | — | US | disclosed |
| WO-1999055656-A1 | PROCESS FOR PREPARING 4-(SUBSTITUTED PHENYL)-3,4-DIHYDRO-2H-NAPHTHALEN-1-ONES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1999-11-04 | — | — | WO | disclosed |