Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884308 | 0.87 | HTR1B (0.43) | HTR1BALDH1A1TDP1KDM4EHPGD | |
| SCHEMBL5394032 | 0.82 | TSHR (0.45) | HTR1BKCNA3HTR1DTSHRSLC6A4 | |
| SCHEMBL7762993 | 0.82 | ALDH1A1 (0.47) | HTR1BALDH1A1TDP1KDM4EHPGD | |
| SCHEMBL7754728 | 0.82 | HTR1B (0.46) | HTR1BALDH1A1TDP1KDM4EHPGD | |
| SCHEMBL442767 | 0.77 | HTR1B (0.54) | HTR1BALDH1A1TDP1KDM4EHPGD | |
| SCHEMBL29577853 | 0.77 | HTR1B (0.54) | HTR1BALDH1A1TDP1KDM4EHPGD | |
| SCHEMBL4289478 | 0.77 | HTR1B (0.59) | HTR1BALDH1A1TDP1KDM4EHPGD | |
| SCHEMBL15093186 | 0.77 | HTR1B (0.47) | HTR1BALDH1A1TDP1KDM4EHPGD | |
| SCHEMBL7243364 | 0.77 | HPRT1 (0.48) | ALDH1A1TDP1KDM4EHPGDHSD17B10 | |
| SCHEMBL7237089 | 0.76 | HTR1B (0.46) | HTR1BKCNA3HTR1DTSHRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10232344-B2 | Solid sorbent materials for acid-gas separation | RESEARCH TRIANGLE INSTITUTE (US) | 2019-03-19 | — | — | US | claimed |
| US-20170197198-A1 | SOLID SORBENT MATERIALS FOR ACID-GAS SEPARATION | RESEARCH TRIANGLE INSTITUTE (US) | 2017-07-13 | — | — | US | claimed |
| WO-2016011032-A1 | SOLID SORBENT MATERIALS FOR ACID-GAS SEPARATION | RESEARCH TRIANGLE INSTITUTE (US) | 2016-01-21 | — | — | WO | claimed |
| US-10232344-B2 | Solid sorbent materials for acid-gas separation | RESEARCH TRIANGLE INSTITUTE (US) | 2019-03-19 | — | — | US | disclosed |
| US-9932300-B2 | N,N′-diarylurea compounds and N,N′-diarylthiourea compounds as inhibitors of translation initiation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-04-03 | — | — | US | disclosed |
| US-20170197198-A1 | SOLID SORBENT MATERIALS FOR ACID-GAS SEPARATION | RESEARCH TRIANGLE INSTITUTE (US) | 2017-07-13 | — | — | US | disclosed |
| US-20160318857-A1 | N,N'-Diarylurea Compounds and N,N'-Diarylthiourea Compounds as Inhibitors of Translation Initiation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2016-11-03 | — | — | US | disclosed |
| US-9421211-B2 | N,N′-diarylurea compounds and N,N′-diarylthiourea compounds as inhibitors of translation initiation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-08-23 | — | — | US | disclosed |
| WO-2016011032-A1 | SOLID SORBENT MATERIALS FOR ACID-GAS SEPARATION | RESEARCH TRIANGLE INSTITUTE (US) | 2016-01-21 | — | — | WO | disclosed |
| US-20120115915-A1 | N,N'-DIARYLUREA COMPOUNDS AND N,N'-DIARYLTHIOUREA COMPOUNDS AS INHIBITORS OF TRANSLATION INITIATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318857-A1 | N,N'-Diarylurea Compounds and N,N'-Diarylthiourea Compounds as Inhibitors of Translation Initiation | NSUN2, EIF2AK2, RNGTT | HTR1B 2503/4885ALDH1A1 3464/4885TDP1 442/4885 |
| US-20120115915-A1 | N,N'-DIARYLUREA COMPOUNDS AND N,N'-DIARYLTHIOUREA COMPOUNDS AS INHIBITORS OF TRANSLATION INITIATION | NSUN2, EIF2AK2, RNGTT | HTR1B 2503/4885ALDH1A1 3464/4885TDP1 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.