Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.53 |
| ▸ | F2 | P00734 | 4/20 | 0.46 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | HPN | P05981 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752492 | 0.90 | ITGB3 (0.62) | ITGB3ITGA2BF2TMPRSS6MMP2 | |
| SCHEMBL27448418 | 0.90 | ITGB3 (0.62) | ITGB3ITGA2BF2TMPRSS6MMP2 | |
| SCHEMBL7748737 | 0.88 | ITGB3 (0.62) | ITGB3ITGA2BF2TMPRSS6 | |
| SCHEMBL8185170 | 0.84 | ITGB3 (0.54) | ITGB3ITGA2BF2TMPRSS6PLAU | |
| SCHEMBL7752448 | 0.82 | ITGB3 (0.54) | ITGB3ITGA2BF2TMPRSS6 | |
| SCHEMBL7752365 | 0.79 | ITGB3 (0.62) | ITGB3ITGA2BPLAUHPN | |
| SCHEMBL7754731 | 0.79 | ITGB3 (0.51) | ITGB3ITGA2BF2TMPRSS6PLAU | |
| SCHEMBL7752629 | 0.77 | ITGB3 (0.73) | ITGB3ITGA2B | |
| SCHEMBL7752361 | 0.77 | ITGB3 (0.73) | ITGB3ITGA2B | |
| SCHEMBL7748728 | 0.77 | ITGB3 (0.60) | ITGB3ITGA2BF2TMPRSS6MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-B1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMA (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |