Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.54 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | HPN | P05981 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 4/20 | 0.46 |
| ▸ | TMPRSS6 | Q8IU80 | 3/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27464968 | 0.91 | ITGB3 (0.64) | ITGB3ITGA2BPLAUHPNF2 | |
| SCHEMBL8185232 | 0.90 | ITGB3 (0.63) | ITGB3ITGA2BPLAUHPNF2 | |
| SCHEMBL27462389 | 0.90 | ITGB3 (0.63) | ITGB3ITGA2BPLAUHPNF2 | |
| SCHEMBL8189053 | 0.90 | MMP2 (0.52) | ITGB3ITGA2BPLAUHPNITGAV | |
| SCHEMBL7752448 | 0.88 | ITGB3 (0.54) | ITGB3ITGA2BF2TMPRSS6ITGAV | |
| SCHEMBL7748737 | 0.87 | ITGB3 (0.62) | ITGB3ITGA2BF2TMPRSS6ITGAV | |
| SCHEMBL7754743 | 0.84 | ITGB3 (0.53) | ITGB3ITGA2BPLAUHPNF2 | |
| SCHEMBL8188715 | 0.83 | ITGB3 (0.51) | ITGB3ITGA2BITGAV | |
| SCHEMBL8185293 | 0.83 | ITGB3 (0.50) | ITGB3ITGA2BITGAV | |
| SCHEMBL8184995 | 0.82 | ALDH1A1 (0.48) | ITGB3ITGA2BPLAUHPNF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |