Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5712758 | 0.77 | ACHE (0.53) | ACHEBACE1MAOAMAOB | |
| Water SCHEMBL10597680 | 0.76 | ACHE (0.52) | ACHEBACE1MAOAMAOB | |
| SCHEMBL6001632 | 0.74 | ACHE (0.65) | ACHEBACE1 | |
| SCHEMBL10686773 | 0.72 | ACHE (0.68) | ACHEBACE1 | |
| SCHEMBL10702784 | 0.72 | ACHE (0.68) | ACHEBACE1 | |
| SCHEMBL10682296 | 0.72 | ACHE (0.68) | ACHEBACE1 | |
| SCHEMBL7886293 | 0.72 | ALOX5 (0.37) | — | |
| SCHEMBL10702537 | 0.67 | MAPT (0.38) | — | |
| SCHEMBL5712755 | 0.65 | ACHE (0.60) | ACHEBACE1MAOAMAOB | |
| SCHEMBL10602433 | 0.64 | ACHE (0.63) | ACHEBACE1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604278-B1 | Indoline derivatives and dye compositions for keratinic fibres | OREAL (FR) | 2001-02-21 | — | — | EP | disclosed |
| US-5556989-A | HAIR DYES | L'OREAL (FR) | 1996-09-17 | — | — | US | disclosed |
| US-5427588-A | Oxidation hair dyes; 1-oxy- or aminocarbonyl or oxy- or aminothiocarbonylindololines | L'OREAL (FR) | 1995-06-27 | — | — | US | disclosed |
| EP-0604278-A1 | Indoline derivatives and dye compositions for keratinic fibres | L'OREAL (FR) | 1994-06-29 | — | — | EP | disclosed |